PMID: 8951487Nov 1, 1996Paper

Chondromyxoid fibroma-like osteosarcoma: a distinct variant of low-grade osteosarcoma

Histopathology
L T ChowJ C Lee

Abstract

Chondromyxoid fibroma-like osteosarcoma is a recently described, extremely rare subtype of low-grade osteosarcoma. Two such cases were encountered among 102 cases of osteosarcoma seen in the Prince of Wales Hospital, Hong Kong, between 1984 and 1994. The first patient, a 39-year-old woman, presented with a mass in her right maxilla which was resected and mistaken as a myxoma. The tumour recurred locally four years later and she now has extensive local recurrent disease six years after initial presentation and is amenable to support treatment only. The second patient, a 28-year-old man, had a pelvic tumour which recurred in the form of a polypoid left atrial tumour and pulmonary nodules six years after operation. The left atrial tumour recurred one year after operation, and led to sudden death of the patient seven years after initial presentation. Radiologically, the tumours in both cases appeared as expansile osteolytic lesions with erosion of adjacent bone and infiltration into soft tissue. Histologically, they consisted of lobules of spindle, stellate or polygonal tumour cells showing mitotic activity and with moderate nuclear pleomorphism and hyperchromatism, set in a highly myxoid stroma superficially mimicking chondromyxoi...Continue Reading

Citations

Jun 1, 2010·Journal of Maxillofacial and Oral Surgery·Ramen SinhaK Rajkumar
Oct 27, 2010·The American Journal of Surgical Pathology·Elizabeth G DemiccoAndrew E Rosenberg
Aug 5, 1998·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·E J Raubenheimer, C E Noffke
Feb 11, 2005·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·John Hicks
Oct 28, 2011·American Journal of Clinical Pathology·Domenico CorradiCarrie Y Inwards
Dec 27, 2019·Archives of Pathology & Laboratory Medicine·David SusterG Petur Nielsen
Jan 31, 2020·BMC Musculoskeletal Disorders·Jingyu ZhongWeiwu Yao
Dec 10, 2016·Fetal and Pediatric Pathology·Matthew StarkRandall Craver
May 8, 2021·Journal of the American Society of Cytopathology : JASC·Sintawat WangsiricharoenSyed Z Ali
Dec 22, 2004·Journal of Surgical Oncology·Saral S DesaiManish Agarwal

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