Choosing between velocity-time-integral ratio and peak velocity ratio for calculation of the dimensionless index (or aortic valve area) in serial follow-up of aortic stenosis.

International Journal of Cardiology
Judith A FinegoldDarrel P Francis

Abstract

It remains unclear which echocardiographic measure is most suitable for serial measurement in real-world aortic stenosis (AS) follow-up. We determine whether the dimensionless index (DI) between aortic valve and left ventricular outflow tract velocities is measured more consistently using velocity-time-integral (VTI) or peak velocities (V(peak)) in real life. Serial echocardiograms acquired within 6 months in subjects with AS were analysed with blinding, to compare the variability over time of DI calculated using V(peak), with that of DI calculated using VTI. Paired echocardiograms, acquired on average 72 days apart, were analysed from 70 patients with a range of severities of AS (59% severe). DI, calculated using either V(peak) or VTI, did not significantly change over this short time. Coefficient of variation was significantly better when DI was calculated using V(peak) than VTI (12.6 versus 25.4%, p<0.0001). The variabilities of mean and peak trans-aortic valve 4v(2) and left ventricular outflow tract VTI were no better: 26.9%, 19.1% and 22.1% respectively. Serially-followed variables require minimal noise to maximise detection of genuine change. For AS surveillance, calculating DI--or effective orifice area--from the ratio ...Continue Reading

References

Jul 15, 1992·The American Journal of Cardiology·P FaggianoC Rusconi
Mar 1, 1989·Journal of the American College of Cardiology·C M OttoC L Gardner
Feb 1, 1995·Journal of the American College of Cardiology·S J BrenerW J Stewart
Nov 26, 2002·Journal of the American College of Cardiology·Michael F BellamyMaurice Enriquez-Sarano
Feb 20, 2004·European Heart Journal·Raphael RosenhekHelmut Baumgartner
Feb 26, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Lindsay A SmithDavid B Northridge
Jun 10, 2005·The New England Journal of Medicine·S Joanna CowellUNKNOWN Scottish Aortic Stenosis and Lipid Lowering Trial, Impact on Regression (SALTIRE) Investigators
Dec 25, 2007·European Heart Journal·Jan MinnersNikolaus Jander
Sep 4, 2008·The New England Journal of Medicine·Anne B RossebøUNKNOWN SEAS Investigators
Sep 9, 2008·The American Journal of Cardiology·Francesco Antonini-CanterinGian Luigi Nicolosi
Jan 10, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Helmut BaumgartnerUNKNOWN European Association of Echocardiography
Sep 18, 2010·JACC. Cardiovascular Imaging·Simon BinerRobert J Siegel
Dec 24, 2011·Korean Circulation Journal·Jeong-Sook SeoJae-Kwan Song

❮ Previous
Next ❯

Citations

Nov 19, 2013·International Journal of Cardiology·UNKNOWN International Working Group on Quantitative Optimization:Darrel P Francis
Apr 29, 2014·IEEE Transactions on Medical Imaging·Massoud ZolgharniDarrel P Francis
Jul 9, 2013·International Journal of Cardiology·Darrel P FrancisGraham D Cole
Oct 19, 2017·BMC Cardiovascular Disorders·Artan AhmetiGani Bajraktari

❮ Previous
Next ❯

Related Concepts

Related Feeds

Ataxia telangiectasia (MDS)

Ataxia telangiectasia is a rare neurodegenerative diseases caused by defects in the ATM gene, which is involved in DNA damage recognition and repair pathways. Here is the latest research on this autosomal recessive disease.