PMID: 11903173Mar 21, 2002Paper

Chordoma: review of clinicoradiological features and factors affecting survival

Australasian Radiology
M Y Soo

Abstract

This study reviews the clinicoradiological features of cranial and sacrospinal chordomas and identifies factors affecting survival. Nineteen patients seen between January 1980 and December 2000 with histopathological diagnosis of chordomas were retrospectively reviewed with reference to clinical presentation, imaging features, treatment modalities and post-therapy status. Eight had tumours in the skull base while 11 patients had spinal and sacrococcygeal lesions. Surgical resection was performed in 16 patients whose subsequent natural history was used to identify clinical indicators that may influence survival. Completeness of resection, age, gender and postoperative irradiation were subjected to analysis using the Cox proportional hazard models. Kaplan-Meir survival curves illustrate the survival distributions. Diplopia and facial pain are prime clinical presentations in cranial lesions, while extremity weakness and a sacrogluteal mass are common complaints in the sacrospinal group. Lesional calcifications are present in 40% while an osteolytic soft tissue mass is detectable by CT in all cases. Heterogeneous signals and internal septations on T2-weighted MRI are predominant features. In sacrospinal tumours, complete excision w...Continue Reading

References

Jan 1, 1975·Journal of Surgical Oncology·I M Ariel, C Verdu
Apr 1, 1990·AJR. American Journal of Roentgenology·L H Wetzel, E Levine
Jan 1, 1988·Radiology·G SzeT H Newton
Jan 1, 1987·Skeletal Radiology·J SmithR C Marcove
Jul 1, 1985·AJR. American Journal of Roentgenology·D I RosenthalT J Brady
Jan 1, 1994·Clinical Oncology : a Journal of the Royal College of Radiologists·N AshwoodM I Saunders
Mar 1, 1994·The British Journal of Surgery·K M AnsonA C Montgomery
Jan 1, 1993·British Journal of Neurosurgery·L WatkinsH A Crockard
May 1, 1993·Journal of Neurosurgery·P A ForsythD G Piepgras
Jul 1, 1996·World Journal of Surgery·R Y Chandawarkar
Mar 24, 1998·Australasian Radiology·P S PrabhakaranN Anantha
Dec 2, 1998·Australasian Radiology·A HoldenP Robins
Jan 23, 1999·Neurosurgery·J E YorkZ L Gokaslan

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Citations

Oct 14, 2004·Skeletal Radiology·Mi Sook SungDonald Resnick
Mar 16, 2006·Clinical Rheumatology·Christian Hubert RouxLianna Euller-Ziegler
Jun 14, 2005·Cancer Genetics and Cytogenetics·Petter BrandalSverre Heim
Jan 25, 2005·Seminars in Ultrasound, CT, and MR·Kambiz MotamediLeanne L Seeger
Sep 23, 2003·Current Opinion in Otolaryngology & Head and Neck Surgery·Michele St Martin, Samuel C Levine
Dec 1, 2012·Journal of Medical Case Reports·Jaber AlshammariKishore Sandu
Mar 28, 2006·Neurologia Medico-chirurgica·Carsten StüerCarlo Schaller
May 4, 2010·Journal of Neurosurgery. Spine·Liu Xue-SongZhang Heng
Aug 28, 2012·Journal of Neurosurgery. Spine·Yu WangLiangzhe Wang
May 18, 2012·TheScientificWorldJournal·Gandikota GirishDavid Jamadar
Jul 11, 2003·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Eren ErdemOssama Al-Mefty
Feb 19, 2013·World Neurosurgery·Youssef YakkiouiJacobus J Van Overbeeke
Aug 1, 2008·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Gloria VergaraAlejandro de la Torre
Dec 6, 2014·Radiologic Clinics of North America·Bruno A Policeni, Wendy R K Smoker
May 6, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·B KayaniT W R Briggs
Nov 6, 2009·The British Journal of Radiology·P M BrennanM O Fitzpatrick
Mar 19, 2009·Acta neurochirurgica·Jeroen R CoppensWilliam T Couldwell
Jul 31, 2013·Neurocirugía·Borja Jesús Hernández GarcíaAlvaro Gómez de la Riva
Aug 2, 2011·Journal of Vascular and Interventional Radiology : JVIR·Jing-Yue GuanYan-Hao Li
Jan 1, 2008·Reumatología clinica·Eva Pérez PampínJuan José Díaz Garel
Oct 17, 2008·Radiologic Clinics of North America·Hsueh Wen CheongGiuseppe Guglielmi
May 10, 2008·Neuroimaging Clinics of North America·Bruno A Policeni, Wendy R K Smoker
Dec 11, 2007·International Journal of Radiation Oncology, Biology, Physics·Hans Peter RutzBeate Timmermann
Nov 7, 2006·International Journal of Radiation Oncology, Biology, Physics·Hans Peter RutzGudrun Goitein
Jun 28, 2015·World Neurosurgery·Babar KayaniTimothy W R Briggs
Apr 27, 2011·ANZ Journal of Surgery·Farhan AhsanGrahame S Inglis
Nov 3, 2004·International Journal of Radiation Oncology, Biology, Physics·Hiroshi IgakiYasuyuki Akine
Apr 29, 2005·Journal of the American Academy of Dermatology·Adam I RubinGeorge Niedt
Mar 21, 2015·Current Problems in Diagnostic Radiology·Michael Charles BurkeAmeet Singh
Jun 25, 2013·Cancer Biology & Therapy·Menghang XiaChristopher P Austin
Jun 8, 2017·Disability and Rehabilitation·Sasha E KnowltonFrancis Hornicek
Jul 17, 2010·Clinical Orthopaedics and Related Research·Pietro RuggieriMario Mercuri
Jun 28, 2008·Clinical Orthopaedics and Related Research·S A HannaA Saifuddin
Jul 20, 2005·Australasian Radiology·F M MacleanT Ng
May 3, 2008·The Journal of Bone and Joint Surgery. British Volume·S A HannaT W R Briggs
Oct 30, 2015·Korean Journal of Spine·Seon Chun KimSang Min Youn
May 29, 2014·Neurosurgery·Babar KayaniTimothy W R Briggs
Nov 24, 2019·Journal of Surgical Oncology·Matthew T HoudekJay S Wunder
Jul 14, 2011·British Journal of Neurosurgery·Brian J JianAndrew T Parsa
Feb 9, 2019·Journal of Surgical Oncology·Matthew T HoudekUNKNOWN Other Members of the Sacral Tumor Society
May 8, 2019·Rinshō shinkeigaku = Clinical neurology·Shoichiro AndoNobuya Fujita

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