Chorion laeve accreta - Another manifestation of morbid adherence

Placenta
T Y KhongDebra S Heller

Abstract

Smooth muscle in the decidua of fetal membranes (membrane myofibers, MMF) is not mentioned in standard textbooks. The current report presents collected observations on 52 patients with MMF at 2 institutions between 2004 and 2017 - including placentas, postpartum curettages, and hysterectomies. Clinical presentations include observation of adherent membranes during delivery, disrupted and incomplete membranes in placentas submitted for examination, postpartum bleeding associated with retained fetal membranes, association with membrane hematomas and membrane hemosiderin, morbidly adherent fetal membranes in hysterectomies; and association with grossly adherent pieces of tissue or nodules in fetal membranes. Although MMF can be an incidental microscopic observation in a routine placenta, the suggested diagnostic terminology when there are clinical and/or gross presentations is Chorion Laeve Accreta (ChLA). Further study is needed but MMF appears to be the fetal membrane counterpart of BPMF(basal plate myofibers), possibly due to damage of subjacent myometrium by trophoblastic proteases, so that shear stress during delivery causes myofibers to come out attached to the decidua of fetal membranes. Neither the prevalence of MMF, nor i...Continue Reading

References

Jul 1, 1987·Placenta·T Y Khong, W B Robertson
Jul 20, 2007·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Jerzy Stanek, Zarius Drummond
Sep 24, 2013·Reproductive Biomedicine Online·Charlotte H E WeimarNick S Macklon
Aug 13, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·E S MillerL M Ernst
Oct 23, 2015·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Stewart F Cramer, Debra S Heller
Mar 23, 2017·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Stewart F Cramer, Debra S Heller
Aug 16, 2017·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Linda M ErnstEmily S Miller
Sep 16, 2017·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Debra S Heller, Fadi Hatem
Nov 21, 2017·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Rachel WyandDebra S Heller

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Citations

Dec 28, 2018·Fetal and Pediatric Pathology·Debra S HellerStewart Cramer
Mar 20, 2019·Fetal and Pediatric Pathology·Stewart CramerDebra S Heller
May 18, 2020·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Jonathan L HechtDebra S Heller
Dec 11, 2020·Obstetrics and Gynecology International·Jerzy Stanek
May 14, 2021·Biology of Reproduction·Elisa T ZhangJulie C Baker
Sep 30, 2021·American Journal of Perinatology·Jerzy Stanek

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