Chorionic bump in pregnant patients and associated live birth rate: a systematic review and meta-analysis

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Elizabeth Kagan ArleoRobert N Troiano

Abstract

A chorionic bump on first-trimester sonography has been considered a risk factor for nonviability in pregnant patients with this rare finding, although the strength of this association has recently been questioned. We performed a systematic review and meta-analysis to summarize the association between a chorionic bump and nonviability. A comprehensive literature search was performed. We included all studies except case reports. A meta-analysis was performed using a random-effects model. After screening 5 studies, 2 studies with a total of 67 patients met inclusion criteria. These were combined with a study (n = 52) from our institution. Overall, the live birth rate was 62% (74 of 119). Fifty-one chorionic bump pregnancies were otherwise normal (ie, pregnancies in which a gestational sac, a yolk sac, and an embryo with a heartbeat was seen at some point), and in this subset, the live birth rate was 83% (42 of 51). There was no significant relationship found between vaginal bleeding and live birth (P = .857); there was no significant difference in bump volume between live birth and no live birth (P = .198); and for the subset analysis of pooled odds ratios for the relationship between live birth and history of infertility, there ...Continue Reading

References

Jun 1, 1995·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·P M Doubilet, C B Benson
May 30, 2006·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Robert D HarrisSophia Ouhilal
Jul 28, 2009·Journal of Clinical Epidemiology·David MoherUNKNOWN PRISMA Group
May 3, 2011·Human Reproduction·George I PapaioannouKypros H Nicolaides
Jun 28, 2011·AJR. American Journal of Roentgenology·Elizabeth Kagan Arleo, Robert N Troiano
Jun 5, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Y SanaJ A Ross
Oct 11, 2013·The New England Journal of Medicine·Peter M DoubiletIlan E Timor-Tritsch
Feb 11, 2014·Ginekologia polska·Piotr WegrzynMirosław Wielgoś
Dec 30, 2014·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Elizabeth Kagan Arleo, Robert N Troiano

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Citations

Apr 19, 2018·BMJ Case Reports·Rita Simões CarvalhoFrancisco Valente
Jul 18, 2020·BMJ Case Reports·Kelly McCarterNigel Pereira
Aug 2, 2018·Journal of Medical Ultrasound·Ladan Younesi, Razieh Shahnazari
Sep 19, 2020·American Journal of Reproductive Immunology : AJRI·Yu LuMin Ren
Dec 18, 2020·Curēus·Amman YousafAmal Alobadli
Jun 5, 2021·Journal of Clinical Ultrasound : JCU·Hisham M MirghaniShweta Uppal

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