Chorionic gonadotropin and uterine dialogue in the primate

Reproductive Biology and Endocrinology : RB&E
Paula CameoAsgerally T Fazleabas

Abstract

Implantation is a complex spatio-temporal interaction between the growing embryo and the mother, where both players need to be highly synchronized to be able to establish an effective communication to ensure a successful pregnancy. Using our in vivo baboon model we have shown that Chorionic Gonadotropin (CG), as the major trophoblast derived signal, not only rescues the corpus luteum but also modulates the uterine environment in preparation for implantation. This response is characterized by an alteration in both the morphological and biochemical activity in the three major cell types: luminal and glandular epithelium and stromal fibroblasts. Furthermore, CG and factors from the ovary have a synergistic effect on the receptive endometrium. Novel local effects of CG which influence the immune system to permit the survival of the fetal allograft and prevent endometrial cell death are also discussed in this review. An alternate extracellular signal-regulated kinase (ERK) activation pathway observed in epithelial endometrial cells and the possibility of differential expression of the CG/LH-R isoforms during gestation, open many questions regarding the mechanism of action of CG and its signal transduction pathway within the primate ...Continue Reading

References

Jul 1, 1976·The Journal of Pathology·D Hopwood, D A Levison
Feb 1, 1990·The Journal of Clinical Endocrinology and Metabolism·E ReshefJ L Luborsky
Jan 1, 1990·Cytogenetics and Cell Genetics·M F Rousseau-MerckR Berger
Oct 1, 1988·Proceedings of the Society for Experimental Biology and Medicine·J D Jensen, W D Odell
Nov 1, 1986·The Journal of Clinical Endocrinology and Metabolism·M A FeinmanJ F Strauss
Jan 1, 1986·Annals of the New York Academy of Sciences·A Psychoyos
Jan 1, 1987·Anatomy and Embryology·R TararaJ G Else
May 1, 1994·The Journal of Clinical Endocrinology and Metabolism·P LichtT G Day
Jun 1, 1993·Endocrine Reviews·D L Segaloff, M Ascoli
Dec 1, 1995·Human Reproduction·G ChaouatC Lelaidier
Jun 1, 1996·The Journal of Clinical Endocrinology and Metabolism·J E PabonC V Rao
Apr 29, 1998·The Journal of Clinical Endocrinology and Metabolism·H M HausermannA T Fazleabas
Apr 29, 1998·Annual Review of Physiology·M L Dufau
Dec 2, 1998·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·K S RyuT H Ji
Mar 3, 1999·Proceedings of the National Academy of Sciences of the United States of America·A T FazleabasJ B Miller
Oct 21, 1999·Journal of Cellular Physiology·L Miele, B Osborne
Apr 15, 2000·Frontiers in Neuroendocrinology·F A Antoni
Aug 15, 2000·Molecular and Cellular Endocrinology·T E VaskivuoJ S Tapanainen
Dec 26, 2001·Archives of Medical Research·S SrisuparpA T Fazleabas
Dec 26, 2001·Journal of the Society for Gynecologic Investigation·E A Stewart
Jan 21, 2003·Biology of Reproduction·Santha SrisuparpAsgerally T Fazleabas

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Citations

Jul 10, 2007·Journal of Assisted Reproduction and Genetics·Yalda AfsharAsgerally T Fazleabas
Aug 17, 2011·Reviews in Endocrine & Metabolic Disorders·Prajna Banerjee, Asgerally T Fazleabas
Nov 13, 2008·Endocrine·Pablo Dominguez-LopezFabian Arechavaleta-Velasco
May 2, 2012·Genome Biology and Evolution·Zhuo-Cheng HouDerek E Wildman
Oct 24, 2008·Human Reproduction Update·S F de Medeiros, R J Norman
Jul 12, 2008·Annual Review of Cell and Developmental Biology·Saara M Rawn, James C Cross
Oct 20, 2005·Reproductive Biology and Endocrinology : RB&E·Luana PaulesuFelice Petraglia
Jun 1, 2009·Journal of Toxicologic Pathology·Zaher A RadiDale L Morris
Feb 16, 2007·The Journal of Perinatal & Neonatal Nursing·Elizabeth Stevens, Jennifer Gilbert-Cohen
Feb 25, 2010·Reproduction : the Official Journal of the Society for the Study of Fertility·H SinghJ D Aplin
Nov 27, 2008·American Journal of Reproductive Immunology : AJRI·Antonis MakrigiannakisAris Antsaklis
Feb 5, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Anna G JankowskaProf Jerzy B Warchol
Oct 27, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Sarah BerndtJean-Michel Foidart
Oct 27, 2010·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Stefano AngioniRafaele L Sciorsci
Sep 13, 2008·Endocrinology·Julieta L MaymóCecilia L Varone
Oct 1, 2010·Reproduction in Domestic Animals = Zuchthygiene·M D Saenz-de-JuanoJ S Vicente
Mar 19, 2020·International Journal of Molecular Sciences·Maria Ariadna Ochoa-Bernal, Asgerally T Fazleabas
Mar 20, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Claudia Castruita-De la RosaMargarita L Martinez-Fierro
May 16, 2006·Trends in Endocrinology and Metabolism : TEM·Antonis MakrigiannakisGeorge P Chrousos
May 22, 2010·Molecular and Cellular Endocrinology·Liina NagirnajaMaris Laan

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