PMID: 6403410Jan 1, 1983Paper

Choroidal ganglioneuroma in neurofibromatosis

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
J J WoogD Horns

Abstract

A twenty-one year old female with previously unsuspected neurofibromatosis presented for evaluation of a blind painful eye. Histopathologic examination of the enucleated specimen revealed choroidal thickening with ovoid bodies and proliferation of connective tissue with pigment-containing cells and ganglion-like cells. Electron microscopic study of the latter cell population revealed typical morphologic features of ganglion cells, including numerous electron-dense intracellular granules and an abundance of mitochondria and rough endoplasmic reticulum. These pathologic findings were interpreted as consistent with the diagnosis of choroidal ganglioneuroma occurring in the context of ocular neurofibromatosis. The literature concerning this unusual tumor is reviewed and the possible relationship of this lesion to neurofibromatosis and other disorders of neural cresent proliferation are briefly discussed.

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Citations

Mar 25, 2014·The Kaohsiung Journal of Medical Sciences·Gonca OzgunBulent Yazici
Dec 10, 2014·The British Journal of Ophthalmology·Solmaz AbdolrahimzadehSanti Maria Recupero
Mar 13, 2016·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Marwah M AbdulkaderJose M Bonnin
Sep 24, 2015·Ophthalmic Plastic and Reconstructive Surgery·Ingrid ChangJing Zhang
Sep 5, 2014·Ophthalmic Plastic and Reconstructive Surgery·Sunali GoyalJohn D Pemberton
Jun 7, 2012·Korean Journal of Ophthalmology : KJO·Yong Soo Byun, Young Hoon Park
Apr 1, 2010·Retinal Cases & Brief Reports·Szilárd KissFrederick A Jakobiec
May 17, 2014·Ophthalmic Plastic and Reconstructive Surgery·Bülent YaziciSaduman B Adim
May 27, 2020·Journal of Ophthalmology·Zhaoxin JiangXiaoyan Ding
May 20, 2003·Acta Ophthalmologica Scandinavica·Yasurou KoyamaAkihiro Ohira
May 17, 2011·European Journal of Ophthalmology·Kan IshijimaSusumu Ishida
Aug 31, 2019·Dermatologic Clinics·Benjamin Becker, Roy E Strowd
Dec 15, 2020·BMC Ophthalmology·Zhaoxin JiangXiaoyan Ding
Oct 31, 2017·Survey of Ophthalmology·Michael KinoriJanice Lasky Zeid

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