Choroidal maps in non-exudative age-related macular degeneration

The British Journal of Ophthalmology
Vittorio CapuanoGiuseppe Querques

Abstract

To compare choroidal thickness maps (CMs) in patients with non-exudative age-related macular degeneration (AMD) and control subjects using swept source optical coherence tomography (Swept-OCT). CMs were automatically measured in the different Early Treatment of Diabetic Retinopathy Study (ETDRS) sectors in eyes with early non-exudative AMD (early AMD) (large soft drusen: group 1; reticular pseudodrusen: group 2 and variable combination of large soft drusen and reticular pseudodrusen: group 3), late non-exudative AMD/geographic atrophy (GA) (late AMD) (group 4) and control subjects (group 5). Fundus autofluorescence (FAF) images were overlaid to sectorial CMs in late-AMD group (group 4). A total of 90 eyes (90 patients, 79.7±8.34 years old) were included. CMs were significantly reduced in early-AMD group 2 and 3 and late-AMD group 4 compared with control subjects in group 5 and early-AMD group 1 (large soft drusen alone) for each ETDRS sectors (p<0.05). No difference in CMs was found by comparing group 2 with 3 and group 2 and 3 with group 4. No statistical differences in CMs were found among ETDRS sectors with >50% absence of FAF ('Hypo FAF' sectors) resulting from retinal atrophy versus ≤50% absence of FAF ('hyper/iso FAF' sec...Continue Reading

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Citations

Mar 21, 2016·Survey of Ophthalmology·Sobha SivaprasadUNKNOWN Moorfields UCL AMD Consortium
Oct 25, 2016·Ophthalmology·Rebecca J SardellMargaret A Pericak-Vance
Oct 30, 2018·Investigative Ophthalmology & Visual Science·Samuel T-H ChiangJohn R Phillips
Apr 28, 2020·European Journal of Ophthalmology·Raffaella RosaMassimo Nicolò
May 13, 2020·Investigative Ophthalmology & Visual Science·Vincenzo ParisiMariacristina Parravano
Nov 19, 2019·Translational Vision Science & Technology·Enrico BorrelliGiuseppe Querques
Feb 6, 2020·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Mei ZhaoAndrew K C Lam
Nov 17, 2016·International Journal of Retina and Vitreous·Fabio Lavinsky, Daniel Lavinsky
Oct 14, 2021·Investigative Ophthalmology & Visual Science·Ying V LiuMandeep S Singh

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