Choroidal thickness in macular telangiectasia type 2

Retina
Jay ChhablaniPodili Srinivas Rao

Abstract

To assess the choroidal thickness changes in eyes with macular telangiectasia Type 2 and their relationship with the integrity of outer retinal structures and visual acuity. This is a prospective observational study that included 81 eyes (41 subjects) with macular telangiectasia Type 2, including 21 women who underwent enhanced depth choroidal imaging. The choroidal thickness measurements were made at the fovea and at 5 points with an interval of 500 μm in both directions, nasal and temporal from the fovea, and were compared with age-matched healthy subjects. Masked observers assessed the outer retinal structure integrity. Stepwise regression was used to find the relationship between age, spherical equivalent, central macular thickness, integrity of the inner segment/outer segment junction, external limiting membrane integrity, and subfoveal choroidal thickness (SFCT). The mean age of the subjects was 55.2 ± 7.8 years in study subjects. The mean SFCT was 274.6 ± 45.7 μm. There was no significant difference between the SFCT in eyes with macular telangiectasia Type 2 and age-matched healthy subjects (P = 0.38). There was no correlation between the visual acuity (r = 0.008); integrity of inner segment/outer segment (r = 0.54); ext...Continue Reading

References

Jun 10, 2004·Retina·Frederick H DavidorfRobert B Chambers
Apr 12, 2006·Archives of Ophthalmology·Lawrence A YannuzziBarbara Blodi
Oct 13, 2006·Archives of Ophthalmology·Alain GaudricBelkacem Haouchine
Mar 11, 2008·Investigative Ophthalmology & Visual Science·Peter Charbel IssaHendrik P N Scholl
Feb 24, 2009·Experimental Eye Research·Peter Charbel IssaTos T J M Berendschot
Sep 30, 2010·PloS One·Peter Charbel IssaHendrik P N Scholl
Jul 26, 2011·European Journal of Ophthalmology·Jay Kumar Chhablani, Raja Narayanan
Dec 20, 2011·European Journal of Ophthalmology·Wei ChenHong Zhang
Feb 23, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jay Kumar ChhablaniWilliam Freeman
Sep 11, 2012·Clinical & Experimental Ophthalmology·Lauren N AytonChi D Luu
Dec 12, 2012·Progress in Retinal and Eye Research·Peter Charbel IssaHendrik P N Scholl
Jun 19, 2013·Ophthalmology·Michael B PownerMarcus Fruttiger
Oct 26, 2013·The British Journal of Ophthalmology·Ignacio Flores-MorenoJose Maria Ruiz-Moreno

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Citations

Jul 4, 2015·Indian Journal of Ophthalmology·Jay ChhablaniSubhadra Jalali
Apr 21, 2018·European Journal of Ophthalmology·Vinod KumarPrasad Gupta
Nov 26, 2019·European Journal of Ophthalmology·Sumit Randhir SinghJay Chhablani
Dec 19, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Vinod KumarPradeep Kumar

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