Choroidal thickness maps from spectral domain and swept source optical coherence tomography: algorithmic versus ground truth annotation.

The British Journal of Ophthalmology
Ana-Maria PhilipU Schmidt-Erfurth

Abstract

The purpose of the study was to create a standardised protocol for choroidal thickness measurements and to determine whether choroidal thickness measurements made on images obtained by spectral domain optical coherence tomography (SD-OCT) and swept source (SS-) OCT from patients with healthy retina are interchangeable when performed manually or with an automatic algorithm. 36 grid cell measurements for choroidal thickness for each volumetric scan were obtained, which were measured for SD-OCT and SS-OCT with two methods on 18 eyes of healthy volunteers. Manual segmentation by experienced retinal graders from the Vienna Reading Center and automated segmentation on >6300 images of the choroid from both devices were statistically compared. Model-based comparison between SD-OCT/SS-OCT showed a systematic difference in choroidal thickness of 16.26±0.725 μm (p<0.001) for manual segmentation and 21.55±0.725 μm (p<0.001) for automated segmentation. Comparison of automated with manual segmentations revealed small differences in thickness of -0.68±0.513 μm (p=0.1833). The correlation coefficients for SD-OCT and SS-OCT measures within eyes were 0.975 for manual segmentation and 0.955 for automatic segmentation. Choroidal thickness measurem...Continue Reading

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Citations

Sep 9, 2017·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Ane Pérez-SarrieguiGema Rebolleda
Mar 21, 2020·Investigative Ophthalmology & Visual Science·Sara TouhamiAlain Gaudric
Apr 25, 2020·Diagnostics·Elvira Orduna-HospitalIsabel Pinilla
Sep 2, 2019·The British Journal of Ophthalmology·Christoph MitschUrsula Margarethe Schmidt-Erfurth
Sep 19, 2019·Scientific Reports·Jason KugelmanMichael J Collins
Dec 7, 2018·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Hosein Hoseini-YazdiDavid Alonso-Caneiro
Jul 15, 2020·Current Eye Research·Isabel PinillaElvira Orduna-Hospital
May 22, 2019·Translational Vision Science & Technology·Helena Giannakaki-ZimmermannUNKNOWN on behalf of the Bern Photographic Reading Center
Feb 6, 2020·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Mei ZhaoAndrew K C Lam
Aug 25, 2020·Cornea·Matthias F KriegelMaria A Woodward

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