Chromaffin cells in the amphibian urodele Triturus carnifex show ultrastructural features indicative of a vesicle-mediated mode of cell degranulation

The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
E CrivellatoAntonio De Luca

Abstract

Recently, suggestive evidence for piecemeal degranulation (PMD), a particulate pattern of cell secretion accomplished by vesicle-mediated extracellular transport of granule-stored material, has been provided by electron microscopy investigations in chromaffin cells of different vertebrate species. In this study, chromaffin tissue from the interrenal gland of the amphibian urodede Triturus carnifex has been investigated by quantitative transmission electron microscopy in search for ultrastructural clues indicative of a vesicle-mediated mode of cell degranulation. Interestingly, a single type of chromaffin cell is recognizable in T. carnifex, which undergoes seasonal variations in its adrenaline and noradrenaline granule ratio according to an annual cycle that matches the trend of changes in secondary sexual characters. In this study, we looked for a series of ultrastructural changes regarded as highly specific for PMD. We calculated the percentage of (i) resting, unaltered granules (type 1 granules); (ii) granules with changes indicative of progressive release of secretory materials, that is, granules with lucent areas in their cores, reduced electron density, disassembled matrices, and residual cores (type 2 granules); and (iii...Continue Reading

References

Jul 22, 1991·Biochimica Et Biophysica Acta·R D Burgoyne
Sep 1, 1995·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·W Hanke, W Kloas
Jun 1, 1997·General and Comparative Endocrinology·B GfellW Hanke
Jan 14, 2003·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Enrico CrivellatoDomenico Ribatti
Mar 29, 2003·Physiological Reviews·Robert D Burgoyne, Alan Morgan
Dec 25, 2003·International Review of Cytology·Valentina Patrizia Gallo, Annalena Civinini
Feb 26, 2004·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Enrico CrivellatoDomenico Ribatti
Feb 1, 2005·Journal of Anatomy·Enrico CrivellatoCarlo Alberto Beltrami
Jun 1, 2005·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Ann M Dvorak
Feb 24, 2006·Proceedings of the National Academy of Sciences of the United States of America·Lisa A SpencerPeter F Weller
Sep 12, 2006·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Enrico CrivellatoValentina Patrizia Gallo
Apr 1, 1991·Journal of Morphology·V Laforgia, A Capaldo
Sep 1, 1986·Journal of Morphology·Elena Grassi Milano, Fiorenza Accordi

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Citations

Mar 27, 2010·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Enrico CrivellatoDomenico Ribatti

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