Chromatic-contrast threshold impairment in diabetes

Eye
S J TregearA G Casswell

Abstract

A prospective study was carried out to investigate acquired colour-vision deficits in diabetics using an automated, computer-controlled, cathode-ray-tube based test of chromatic contrast. Chromatic-contrast thresholds estimates were measured along both a red/ green (constant S-cone) confusion axis and a tritan (constant M/L-cone) confusion axis for 305 eyes of 305 diabetics. The diabetic data were partitioned into groups based on a clinical categorisation of retinopathy. The diabetic data were compared with both age-matched and 'lens-equated' control data obtained from a bank of 347 normal subjects. Further analysis of differences between diabetic-status groups was performed. Associations between chromatic contrast threshold estimates and age, duration of disease, and severity of both macular oedema and ischaemia were investigated. The diabetic group was found to have significantly reduced chromatic-contrast threshold estimates when compared with normal controls, even in the absence of retinopathy. This reduction in chromatic contrast was predominantly tritanopic in nature. Interestingly, no reduction in red/green chromatic-contrast threshold estimate was found in diabetics without retinopathy. The tritan deficit seen in diabet...Continue Reading

References

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Citations

May 10, 2001·Clinical & Experimental Ophthalmology·E LiethUNKNOWN Penn State Retina Research Group
Dec 17, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Arthur Stevens
Aug 17, 2005·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Katharine E MortlockRachel V North
May 2, 2007·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Sri ThyagarajanH Laidlaw
Oct 5, 2010·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Claudia Feitosa-SantanaDora F Ventura
Jul 25, 2000·The British Journal of Ophthalmology·R S NewsomA G Casswell
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Apr 2, 2015·Indian Journal of Ophthalmology·Inmaculada CabezosVicente Camps
Apr 11, 2003·Diabetologia·B V BuiA J Vingrys
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Feb 27, 2021·Cardiovascular Endocrinology & Metabolism·Sejal LahotiRobert Chilton
Nov 15, 2020·Progress in Retinal and Eye Research·Deoye Tonade, Timothy S Kern

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