journal cover

Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations

Nature

Nov 12, 2013

Yubo ZhangChia-Lin Wei

Abstract

In multicellular organisms, transcription regulation is one of the central mechanisms modelling lineage differentiation and cell-fate determination. Transcription requires dynamic chromatin configurations between promoters and their corresponding distal regulatory elements. It is believ...read more

Mentioned in this Paper

RNA Polymerase II
Fluorescent in Situ Hybridization
Transcriptional Regulation
DNA-Directed RNA Polymerase
Complex (molecular entity)
Transcription, Genetic
Aggregation
Transcription Initiation
Promoter
Gene Expression
22
707
1
Paper Details
References
  • References28
  • Citations102
123
  • References28
  • Citations102
12345...

Similar Papers Found In These Feeds

Lineage Commitment

Lineage commitment is the consolidation of a distinct pattern of gene expression in a cell type distiguising it from its progenitor and other cells derived from its progentior cell. Here is the latest research.

Chromatin Regulators: Differentiation (Keystone)

Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins in cellular differentiation.

General Biology Journal eTOCs

Discover the latest general biology research in this collection of the top biology journals.

Eukaryotic RNA Polymerase II (Keystone)

RNA polymerase II (RNAP II) is a 550 kDa multiprotein complex composed of 12 subunits. Here is the latest research on RNAP II and its role it regulating transcription and transcription-coupled recombination repair.

Eukaryotic RNA Polymerase II

RNA polymerase II (RNAP II) is a 550 kDa multiprotein complex composed of 12 subunits. Here is the latest research on RNAP II and its role it regulating transcription and transcription-coupled recombination repair.

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Enhancers & Gene Expression (Keystone)

Enhancers are short regions of the DNA which can be bound by activator or repressor proteins to affect transcription of a particular gene. This feed focuses on the role of enhancers in regulation of cell-type specific gene expression during development.

Chromatin Regulators: Differentiation

Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins on cellular differentiation.

Nature | Cell | Science

Discover the latest research from the prestigious journals: Nature, Cell, and Science.

Parasite Genetics

Parasite genetics is the study of the genetic material of parasites. Here is the latest research on parasite genetics.

Fluorescence in situ Hybridization (FISH)

Fluorescence in situ hybridization (FISH) is one of the major techniques used to detect of chromosomal aberrations. Here is the latest research.

Nature eTOC

Nature is the world's leading multidisciplinary science journal. Discover the latest research from Nature here.

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Neural Fate Specification

Neural stem cells are self-renewing, multipotent cells that are present in both the embryonic and adult brain. Several factors, including metabolism, have been shown to regulate proliferation, differentiation, and quiescence of neural stem cells. Here is the latest research.

Mechanisms Of Chromatin Transcription (Keystone)

Studying the mechanisms of gene transcription and its regulation is crucial for understanding regulation of development as well as disease. Follow the latest research relating to Patrick Cramer's talk on "Mechanisms of Chromatin Transcription" with this feed.

Enhancers in Development & Diseases (Keystone)

Enhancers are short regions of the DNA which can be bound by activator or repressor proteins to affect transcription of a particular gene. This feed covers the latest research on enhancer function in development and disease.

Embryonic Neural Stem Cells

Embryonic neural stem cells can be used to investigate the effect of different toxins and molecules on the proliferation and differentiation of these cells. Discover the latest research of embryonic neural stem cells here.

Gene Regulation, Differentiation & Reprogramming (Keystone)

This feed focuses on alterations of gene regulation during cell differentation and reprogramming processes. Here is the latest research on gene regulation in differentiation and reprogramming processes.

Related Papers

Biochimica Et Biophysica Acta

Long distance relationships: enhancer-promoter communication and dynamic gene transcription

Biochimica Et Biophysica ActaNovember 6, 2012
Judith Marsman, Julia A Horsfield
Nature

An oestrogen-receptor-alpha-bound human chromatin interactome

NatureNovember 6, 2009
Melissa J FullwoodYijun Ruan
© 2020 Meta ULC. All rights reserved

Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations

Nature

Nov 12, 2013

Yubo ZhangChia-Lin Wei

PMID: 24213634

DOI: 10.1038/nature12716

Abstract

In multicellular organisms, transcription regulation is one of the central mechanisms modelling lineage differentiation and cell-fate determination. Transcription requires dynamic chromatin configurations between promoters and their corresponding distal regulatory elements. It is believ...read more

Mentioned in this Paper

RNA Polymerase II
Fluorescent in Situ Hybridization
Transcriptional Regulation
DNA-Directed RNA Polymerase
Complex (molecular entity)
Transcription, Genetic
Aggregation
Transcription Initiation
Promoter
Gene Expression
22
707
1

Similar Papers Found In These Feeds

Lineage Commitment

Lineage commitment is the consolidation of a distinct pattern of gene expression in a cell type distiguising it from its progenitor and other cells derived from its progentior cell. Here is the latest research.

Chromatin Regulators: Differentiation (Keystone)

Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins in cellular differentiation.

Related Papers

Biochimica Et Biophysica Acta

Long distance relationships: enhancer-promoter communication and dynamic gene transcription

Biochimica Et Biophysica ActaNovember 6, 2012
Judith Marsman, Julia A Horsfield
Nature

An oestrogen-receptor-alpha-bound human chromatin interactome

NatureNovember 6, 2009
Melissa J FullwoodYijun Ruan
Paper Details
References
  • References28
  • Citations102
123
  • References28
  • Citations102
12345...
/papers/chromatin-connectivity-maps-reveal-dynamic/24213634