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Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions

bioRxiv

Feb 26, 2014

Boryana DoyleLeonid A Mirny

Abstract

The classic model of eukaryotic gene expression requires direct spatial contact between a distal enhancer and a proximal promoter. Recent Chromosome Conformation Capture (3C) studies show that enhancers and promoters are embedded in a complex network of looping interactions. Here we use...read more

Mentioned in this Paper

Proximal
Distal
Site
Local
30 Nm Chromatin Fiber
Chromatin Loop
Fiber
Flank (Surface Region)
Facilitation
Enhancer brand
11
14
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Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions

bioRxiv

Feb 26, 2014

Boryana DoyleLeonid A Mirny

PMID: 990003087

DOI: 10.1101/003087

Abstract

The classic model of eukaryotic gene expression requires direct spatial contact between a distal enhancer and a proximal promoter. Recent Chromosome Conformation Capture (3C) studies show that enhancers and promoters are embedded in a complex network of looping interactions. Here we use...read more

Mentioned in this Paper

Proximal
Distal
Site
Local
30 Nm Chromatin Fiber
Chromatin Loop
Fiber
Flank (Surface Region)
Facilitation
Enhancer brand
11
14

Related Papers

Paper Details
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  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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