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Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions

bioRxiv

Feb 26, 2014

Boryana DoyleLeonid A. Mirny

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Abstract

The classic model of eukaryotic gene expression requires direct spatial contact between a distal enhancer and a proximal promoter. Recent Chromosome Conformation Capture (3C) studies show that enhancers and promoters are embedded in a complex network of looping interactions. Here we use...read more

Mentioned in this Paper

Enhancer brand
Gene Expression
Proximal
Study
Simulation
Chromatin
Chromatin Loop
Genomic Stability
Genome
Insulator Elements
11
13
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  • Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions

    bioRxiv

    Feb 26, 2014

    Boryana DoyleLeonid A. Mirny

    PMID: 990003087

    DOI: 10.1101/003087

    Abstract

    The classic model of eukaryotic gene expression requires direct spatial contact between a distal enhancer and a proximal promoter. Recent Chromosome Conformation Capture (3C) studies show that enhancers and promoters are embedded in a complex network of looping interactions. Here we use...read more

    Mentioned in this Paper

    Enhancer brand
    Gene Expression
    Proximal
    Study
    Simulation
    11
    13

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