Chromatin methylation and cardiovascular aging

Journal of Molecular and Cellular Cardiology
Barbara IlliMaurizio C Capogrossi

Abstract

DNA and histone methylation are well characterized epigenetic marks that are altered during the aging process. In aged cells and tissues, DNA cytosine tagging by methylation undergoes the so-called "epigenetic drift", in parallel with a change in the methylated histone profile. Despite the large body of knowledge regarding age-dependent epigenetic changes, there are few reports related to this topic in the cardiovascular field. This review summarizes age-dependent changes in DNA and histone methylation with a specific focus on age-related cardiovascular diseases (CVDs).

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Citations

Apr 15, 2015·Journal of Molecular and Cellular Cardiology·Edward G Lakatta
Oct 18, 2015·Biochimica Et Biophysica Acta·V CassinaF Mantegazza
Jun 24, 2016·BBA Clinical·Alexander Berezin
Apr 30, 2017·Circulation Research·Alessandra MagentaMaurizio C Capogrossi
Jan 27, 2019·Journal of the American Heart Association·Carol C MitchellJames H Stein
Feb 13, 2021·Life Sciences·Xuping LiYuanyuan Cheng
Mar 23, 2021·Frontiers in Cardiovascular Medicine·Beijian ZhangJunbo Ge

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