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Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

Proceedings of the National Academy of Sciences of the United States of America

Oct 29, 2013

Stephen C. J. ParkerNISC Comparative Sequencing Program Authors

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Abstract

Chromatin-based functional genomic analyses and genomewide association studies (GWASs) together implicate enhancers as critical elements influencing gene expression and risk for common diseases. Here, we performed systematic chromatin and transcriptome profiling in human pancreatic isle...read more

Mentioned in this Paper

Enhancer brand
Gene Expression
Luciferases
Associated Study
Regulatory Protein
Chromatin
Locus Control Region
Tissue Specificity
Chromatin Immunoprecipitation
Enhancer Elements, Genetic
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Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

Proceedings of the National Academy of Sciences of the United States of America

Oct 29, 2013

Stephen C. J. ParkerNISC Comparative Sequencing Program Authors

PMID: 24127591

DOI: 10.1073/pnas.1317023110

Abstract

Chromatin-based functional genomic analyses and genomewide association studies (GWASs) together implicate enhancers as critical elements influencing gene expression and risk for common diseases. Here, we performed systematic chromatin and transcriptome profiling in human pancreatic isle...read more

Mentioned in this Paper

Enhancer brand
Gene Expression
Luciferases
Associated Study
Regulatory Protein
8
1
1
408
1
2

Similar Papers Found In These Feeds

Related Papers

Paper Details
References

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