PMID: 2121541Oct 29, 1990Paper

Chromatin structure of Drosophila melanogaster ribosomal genes

FEBS Letters
S V BelikovA D Mirzabekov

Abstract

The chromatin structure of ribosomal genes of D. melanogaster has been studied by crosslinking proteins to DNA. We found that a number of histone contacts with DNA through histidine in the approximately 1 kb-long region surrounding the transcription initiation site, coding regions and the region of 240 bp-long repeats from the intergenic spacers (Alu-repeats) were weakened as compared to the inactive chromatin of the type II insertion. A protein with the molecular mass of 50 kDa (p50), associated with all DNA sequences analysed, has been discovered. Another protein with molecular mass of about 70 kDa (p70) has been found to be specific only for the Alu-repeats.

References

Sep 11, 1979·Nucleic Acids Research·E O Long, I B Dawid
Feb 11, 1986·Nucleic Acids Research·I B Dawid, M L Rebbert
Aug 1, 1985·Molecular and Cellular Biology·D S Gilmour, J T Lis
Nov 1, 1970·In Vitro·G Echalier, A Ohanessian
Nov 11, 1982·Nucleic Acids Research·E S Coen, G A Dover
Apr 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·G M Church, W Gilbert
Jan 1, 1981·Molecular & General Genetics : MGG·E O LongI B Dawid

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Citations

Jan 30, 2007·Nature Structural & Molecular Biology·Hannah S JonesNick J Proudfoot
Sep 24, 1998·Journal of Biomolecular Structure & Dynamics·S Belikov, V Karpov
Mar 15, 1992·European Journal of Biochemistry·S I DimitrovI G Pashev

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