PMID: 2481252Dec 3, 1989Paper

[Chromoendoscopic study of the gastric mucosa].

Orvosi hetilap
I Rácz, E Tóth

Abstract

Chromoendoscopy is an intravital endoscopic mucosa dyeing method. Chromoendoscopical methods suitable for examination of gastric mucosa are described including the steps of premedication as well as the steps of Congo-red and methylene-blue tests. The Congo-red test is capable of estimating the extent of acid-secreting area of gastric mucosa. Large acid secreting areas were found in four-fifth of duodenal ulcer patients with the Congo-red test. An equal ratio of small and large acid-secreting areas was found in gastric ulcer patients. The extent of acid-secreting area decreased parallely with the increase of mucosal atrophy in chronic gastritis patients. Methylene-blue test is suitable for detecting mucosal areas containing intestinal metaplasia and cancer. Intestinal metaplasia was detected histologically in 80% of cases containing mucosal areas stained by methylene-blue test. According to the authors' observations chromoendoscopy is a time consumptive additional method, which requires careful premedication and accurate endoscopic technique. Chromoendoscopy is suitable to detect the accurate places of mucosal biopsies therefore it seems to be a valuable element of morpho-functional diagnostic methods.

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