Chromosomal aberrations, cell suppression and oxidative stress generation induced by metal oxide nanoparticles in onion (Allium cepa) bulb

Metallomics : Integrated Biometal Science
Bilal AhmedJaved Musarrat

Abstract

There has been rapid increase globally in the production of functionally divergent nanoparticles in recent times. The uncontrolled discharge of such nanomaterials is a serious threat to the environment. We assess the impact of various-sized metal oxide nanoparticles (MONPs) on cell cycle progression and induction of oxidative stress in onions. Of these, CuO-NPs and TiO2-NPs significantly reduced the mitotic index (MI) by 28% and 17%, respectively, whereas Al2O3-NPs augmented the MI by 13% compared to untreated onion roots. The NPs internalization into the root tissues followed a dose dependent fashion. Also, several types of chromosomal aberration such as bridges, stickiness, vagrant, broken, and lag chromosomes were noticed. The reactive oxygen species activity of roots growing under CuO-NPs, Al2O3-NPs, and TiO2-NPs was significantly increased by 58, 30, and 10%, respectively. The superoxide dismutases activity (U g-1 FW) of roots increased from 2.4 ± 0.4 (control) to 6.1 ± 0.8 (CuO-NPs), 4.1 ± 0.2 (Al2O3-NPs) and 2.9 ± 0.2 (TiO2-NPs), whereas, catalase activity (mmoles min-1 g-1 FW) was recorded as 18.5 ± 2.1 (CuO-NPs), 15 ± 1.1 (Al2O3-NPs) and 13.8 ± 1 (TiO2-NPs) against 11.4 ± 1 (control). The formazan formed due to superox...Continue Reading

References

Mar 2, 2011·Phytochemical Analysis : PCA·Carlos F Grellet Bournonville, Juan Carlos Díaz-Ricci
Mar 17, 2011·Journal of Agricultural and Food Chemistry·Cyren M RicoJorge L Gardea-Torresdey
Apr 20, 2011·Journal of Hazardous Materials·Mamta KumariNatarajan Chandrasekaran
Aug 5, 2011·Aquatic Toxicology·Guillaume JuhelMarcel A K Jansen
Dec 14, 2011·Journal of Applied Toxicology : JAT·P V PrabhakarMohammed Mahboob
Mar 8, 2012·Apoptosis : an International Journal on Programmed Cell Death·Vyom SharmaAlok Dhawan
Sep 19, 2012·Metallomics : Integrated Biometal Science·Qiang WangYongsheng Chen
Dec 19, 2012·The Science of the Total Environment·Xingmao MaYang Deng
Dec 29, 2012·Archives of Environmental Contamination and Toxicology·Changwei HuMei Li
Mar 12, 2013·Journal of Hazardous Materials·Mohammad FaisalJaved Musarrat
May 22, 2013·Metallomics : Integrated Biometal Science·Qiang WangXingmao Ma
Nov 6, 2013·Metallomics : Integrated Biometal Science·Arnab MukherjeeJorge L Gardea-Torresdey
Sep 10, 2014·TheScientificWorldJournal·Farzad AslaniAli Baghdadi
Jan 31, 2015·Metallomics : Integrated Biometal Science·Franziska SchwabeBernd Nowack
Mar 22, 2015·Environmental Science and Pollution Research International·Ruichang ZhangPeter Christie
Mar 22, 2015·Environmental Science and Pollution Research International·A RajeshwariAmitava Mukherjee
May 4, 2016·Plant Physiology and Biochemistry : PPB·Wenchao DuHongyan Guo
May 21, 2016·Frontiers in Plant Science·Bruno PrintzKjell Sergeant
Sep 8, 2016·Plant Physiology and Biochemistry : PPB·Durgesh Kumar TripathiDevendra Kumar Chauhan
Oct 19, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xiefeng YeZhiqi Shi
Nov 29, 2016·Ecotoxicology and Environmental Safety·Petra CvjetkoBiljana Balen
Jun 25, 2017·Environmental Monitoring and Assessment·Aline A BecaroMarcos David Ferreira
Nov 24, 2017·Frontiers in Chemistry·Indrani Manna, Maumita Bandyopadhyay
Feb 18, 2018·Advances in Experimental Medicine and Biology·Sourabh DwivediJaved Musarrat
Jan 1, 2017·Environmental Science. Nano·Cyren M RicoChristian P Andersen

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Methods Mentioned

BETA
chromosomal aberrations
X-ray
AFM

Software Mentioned

Leica LASAF lite
LASAF lite
Minitab

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