PMID: 1201689Nov 24, 1975Paper

Chromosomal basis of dosage compensation in Drosophila VIII. Faster replication and hyperactivity of both arms of the X-chromosome in males of Drosophila pseudoobscura and their possible significance

Chromosoma
A S Mukherjee, S N Chatterjee

Abstract

3H-thymidine and 3H-uridine labeling patterns of the X-chromosome arms of Drosophila pseudoobscura have been examined autoradiographically. Results show that in all phases of replication, namely, initial, middle and terminal, both arms of the X-chromosome in the male are advanced by one or two steps of 3H-thymidine labeling in comparison with the autosomes, and both arms in the female show more or less similar labeling profile as the autosomes. Both the arms in the male show pale stainability and enlarged width ratio, as reported in other species. The 3H-uridine labeling patterns also reveal that both arms in the male incorporate twice as much precursor as the individual X in the female. Results, therefore, suggest that both arms of the X in D. pseudoobscura are faster replicating and hyperactive in the male, although it is considered that XL is homologous to the X and XR to part of the third chromosome of D. melanogaster.

References

Jan 1, 1973·Annual Review of Genetics·J C Lucchesi
Apr 12, 1974·Nature·J C LucchesiG Maroni
Jan 1, 1973·International Review of Cytology·H D Berendes
Jan 1, 1968·International Review of Cytology·K R Lewis, B John
Apr 1, 1935·Proceedings of the National Academy of Sciences of the United States of America·C C Tan
Sep 1, 1941·Genetics·A H Sturtevant, E Novitski
Mar 1, 1969·Genetics·P D Smith, J C Lucchesi

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Citations

Apr 1, 1996·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·M SteinemannB M Turner
Oct 7, 2000·Journal of Biosciences·G MaheshH A Ranganath

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