PMID: 6974589Apr 1, 1981Paper

Chromosome 14q+ in adult T-cell leukemia

Cancer Genetics and Cytogenetics
I MiyoshiI Kimura

Abstract

Cytogenetic studies were performed on leukemic cells from two patients with adult T-cell leukemia. A 14q+ marker chromosome was found in the peripheral blood leukocytes from patient No. 1 and in a leukemic T-cell line (MT-1) derived from the peripheral blood of patient No. 2. The 14q+ resulted from a t(12;14) in patient No. 1 and from a t(Y;14) in patient No. 2 with a break point at 14q32 in each case. In addition, the leukemic cells from patient No. 1 showed a t(1;7) and a 9q-, while the MT-1 line had numerous structural abnormalities. Thus, it is clear that a 14q+ translocation is not restricted to B-cell neoplasms but occurs in T-cell neoplasms as well.

References

Aug 31, 1979·Brain Research·C GonzalezS J Fidone
Jul 15, 1979·International Journal of Cancer. Journal International Du Cancer·F MitelmanP G Nilsson
Sep 1, 1979·British Journal of Haematology·R BergerG Flandrin
Dec 15, 1979·International Journal of Cancer. Journal International Du Cancer·S FukuharaS Morikawa
Dec 1, 1978·Cancer·A K SullivanB Bain
Mar 29, 1979·The New England Journal of Medicine·A SaxonD W Golde
Jul 15, 1978·International Journal of Cancer. Journal International Du Cancer·S Fukuhara, J D Rowley
Apr 15, 1977·International Journal of Cancer. Journal International Du Cancer·B Kaiser-McCawF Hecht
Jan 15, 1976·International Journal of Cancer. Journal International Du Cancer·L ZechG Klein
Jun 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·B K McCawR L Teplitz
Oct 30, 1971·Lancet·M Seabright
Jun 1, 1970·Experimental Cell Research·T CasperssonC Johansson

❮ Previous
Next ❯

Citations

Jun 1, 1982·Cancer Genetics and Cytogenetics·G Gahrton, K H Robèrt
Aug 1, 1984·Cancer Genetics and Cytogenetics·V Brito-BabapulleD Catovsky
Jan 1, 1991·Cancer Genetics and Cytogenetics·N Sadamori
May 1, 1991·Cancer Genetics and Cytogenetics·R BergerD Vecchione
Sep 13, 2005·Oncogene·Fernando A ProiettiEdward L Murphy
Jul 27, 2006·International Journal of Hematology·Yasushi MatsubarTakashi Uchiyama
Jul 10, 2003·Blood Cells, Molecules & Diseases·Dorothea Zucker-FranklinVesna Najfeld
Sep 21, 2010·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Romain DeschampsStephane Olindo
Jan 1, 1991·Leukemia & Lymphoma·K ItohM Taniwaki
Aug 1, 1983·Cancer·K MiyamotoT Tanaka
Apr 15, 1986·International Journal of Cancer. Journal International Du Cancer·K FujitaH Kamesaki
Sep 15, 1982·International Journal of Cancer. Journal International Du Cancer·Y KanekoJ D Rowley
Feb 1, 1983·The Journal of Dermatology·H IizukaA Wakisaka
Nov 30, 2004·The Journal of Obstetrics and Gynaecology Research·Yoshiya AndoTakenori Toyama

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.