PMID: 11342236May 9, 2001Paper

Chromosome aberrations and sister chromatid exchanges in cultured human lymphocytes treated with sodium metabisulfite, a food preservative

Mutation Research
Eyyüp RencüzoğullariM Topaktaş

Abstract

The aim of this study was to investigate the ability of sodium metabisulfite (SMB) which is used as an antimicrobial substance in food, to induce chromosome aberrations (CA) and sister chromatid exchanges (SCE) in human lymphocytes. SMB-induced CAs and SCEs at all concentrations (75, 150 and 300 microg/ml) and treatment periods (24 and 48h) dose-dependently. However, SMB decreased the replication index (RI) and the mitotic index (MI) at the concentrations of 150 and 300 microg/ml for 24 and 48h treatment periods. This decrease was dose-dependent as well.

References

May 1, 1977·Cancer Letters·M NagaoT Kawachi
Mar 1, 1979·Mutation Research·A MatsuokaM Ishidate
Nov 1, 1978·Mutation Research·M L MaceW Wray
Dec 1, 1992·Mutation Research·Z Meng, L Zhang
Jun 1, 1990·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·R MünznerH W Renner
Jan 1, 1987·Teratogenesis, Carcinogenesis, and Mutagenesis·C Nowak
Jul 1, 1987·Mutation Research·M F LinT C Wang
Nov 1, 1987·Mutation Research·D LucaL Răileanu
Aug 1, 1984·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M IshidateA Matsuoka
Jul 1, 1984·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M M HasegawaN Inui
Apr 1, 1983·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·H W Renner, J Wever

❮ Previous
Next ❯

Citations

Nov 13, 2008·Cytotechnology·Serkan YılmazHüseyin Aksoy
Jun 23, 2004·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Zhengqing Du, Ziqiang Meng
Dec 2, 2011·Journal of Medicinal Chemistry·Satish R MalwalHarinath Chakrapani
Jul 10, 2010·Journal of Biomedicine & Biotechnology·Tülay Aşkin Celik, Ozlem Sultan Aslantürk
Jan 15, 2014·Life Sciences·Xin-Bao WangHong Cui
Aug 30, 2014·Environmental Toxicology and Pharmacology·Edimar Olegário de Campos JúniorLuiz Alfredo Pavanin
Nov 22, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ceren KencebayAysel Agar
Dec 7, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·N ZenginH Aksoy
Jan 22, 2008·Ecotoxicology and Environmental Safety·Guangke Li, Nan Sang
Jun 7, 2008·Environmental and Molecular Mutagenesis·Vânia Maria Sartini Dutra PimentaLuiz Alfredo Pavanin
Jul 1, 2005·Environmental Toxicology and Pharmacology·Ziqiang Meng, Aifang Nie
Feb 1, 2005·Neurotoxicology and Teratology·Vural KüçükatayAysel Ağar
Apr 4, 2014·Nutritional Neuroscience·Ali NoorafshanSaied Karbalay-Doust
May 28, 2015·Regulatory Toxicology and Pharmacology : RTP·Quanxi ZhangZiqiang Meng
Feb 1, 2012·Drug and Chemical Toxicology·Alfredo SantovitoMassimiliano Delpero
Jun 26, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Zhenhua YangZiqiang Meng
Nov 22, 2005·Biochimica Et Biophysica Acta·Aifang Nie, Ziqiang Meng
Mar 11, 2008·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Sifa Türkoğlu
Sep 27, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Aifang Nie, Ziqiang Meng
Oct 30, 2016·Toxicology Mechanisms and Methods·Ozlem OzsoyAysel Agar
Jan 8, 2015·Organic & Biomolecular Chemistry·Satish R Malwal, Harinath Chakrapani
Sep 27, 2006·The International Journal of Neuroscience·Yaşar Gül OzkayaMehmet Zülküf Onal
Nov 12, 2019·Chembiochem : a European Journal of Chemical Biology·Satish R MalwalHarinath Chakrapani
Mar 10, 2005·Mutagenesis·Mustafa CelikResat Kasap
Aug 21, 2012·Toxicology and Industrial Health·Nihal UrenYunus Onal
Sep 7, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xiaohong ChengZhen Li
Jul 1, 2014·Comprehensive Reviews in Food Science and Food Safety·Márcio CarochoIsabel C F R Ferreira
May 16, 2007·Biochemical and Biophysical Research Communications·Aifang Nie, Ziqiang Meng
Jun 27, 2008·Chemico-biological Interactions·Hossein Niknahad, Peter J O'Brien

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.