PMID: 6969702Nov 1, 1980Paper

Chromosome aberrations induced in human lymphocytes by ultrasoft Al (K) and C (K) X-rays

International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine
R P VirsikJ Thacker

Abstract

Induction of structural chromosome aberrations was studied in human peripheral blood lymphocytes irradiated in the unstimulated state with ultrasoft X-rays. Aluminium K X-rays (1.49 ke V) and carbon K X-rays (0.28 ke V) were used. The frequencies of dicentric aberrations and of excess acentric fragments were found to increase approximately linearly with absorbed dose of both radiations. Carbon X-rays were more effective than aluminium X-rays. The corresponding linear yield coefficients for dicentrics are (3.7 X 10(-1)) Gy-1 and (2.2 X 10(-1)) Gy-1 respectively. AT low doses both these radiations are more effective than hard X-rays in producing dicentric aberrations, but at high doses aluminium X-rays are less effective than hard X-rays because of the large positive curvature of the hard X-ray dose-response. The most significant observation of these experiments is that electrons of less than 280 eV, produced by carbon X-rays, are efficient in producing dicentric aberrations. This implies that single local energy events of about 14 ionizations with in less than 7 nm are able to produce exchange aberrations.

References

Apr 30, 1979·Radiation and Environmental Biophysics·A A EdwardsR J Purrott
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Jul 29, 1977·Radiation and Environmental Biophysics·R P VirsikI Hansmann
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Citations

Apr 1, 1989·International Journal of Radiation Biology·D T Goodhead, H Nikjoo
Oct 1, 1986·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·D FrankenbergR E Wilkinson
Jul 1, 1986·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·J Thacker
Apr 1, 1986·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·J ThackerD T Goodhead
Feb 12, 2009·International Journal of Radiation Biology·M S Sasaki
Dec 9, 2008·International Journal of Radiation Biology·A YokoyaR Watanabe
May 1, 1993·International Journal of Radiation Biology·D T GoodheadR Cox
Apr 11, 1991·International Journal of Radiation Biology·C M Meger WellsM N Gould
Sep 1, 1986·Photochemistry and Photobiology·M Inokuti
Apr 28, 2006·International Journal of Radiation Biology·Ganesh Chandra Jagetia, V A Venkatesha
Feb 28, 2008·Radiation Research·Anna LehnertJörg Pawelke
Jan 1, 1990·Radiation and Environmental Biophysics·G MakrigiorgosA I Kassis
Jan 1, 1981·Radiation and Environmental Biophysics·R P Virsik, D Harder
Jun 20, 2002·Radiation Research·Albrecht M Kellerer
Dec 1, 1988·Physics in Medicine and Biology·E A JonesJ Oriel
Mar 1, 1991·Journal of Microscopy·K Shinohara, A Ito
May 1, 1983·Physics in Medicine and Biology·D T Goodhead, D J Brenner
Dec 1, 2000·International Journal of Radiation Biology·F A CucinottaD T Goodhead
May 6, 2003·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·K H ChadwickM J P Brugmans
Jun 1, 1989·Physics in Medicine and Biology·H NikjooH G Paretzke
Nov 1, 1981·Physics in Medicine and Biology·D T GoodheadR Cox

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