Chromosome pairing in inter-racial hybrids of the house musk shrew (Suncus murinus, Insectivora, Soricidae)

Genome Génome / Conseil National De Recherches Canada
P M BorodinS Oda

Abstract

Two chromosome races of the house shrew Suncus murinus that differ from each other for five Robertsonian translocations (8.17, 9.13, 10.12, 11.16, and 14.15), heterochromatic insertions in chromosomes 7 and X, and multiple rearrangements in the Y chromosome were crossed and then intercrossed in captivity to produce a hybrid stock. Electron-microscopic analysis of synaptonemal complexes in fertile and sterile hybrid males was carried out. Meiosis in sterile males did not progress beyond pachytene and was severely disrupted. Meiotic arrest was not determined by structural heterozygosity: heterozygotes for all variant chromosomes distinguishing two parental races were found in both sterile and fertile male hybrids. Fertile hybrids demonstrated an orderly pairing of all chromosomes. In heterozygotes for Robertsonian fusions, completely paired trivalents were formed between the Robertsonian metacentrics and homologous acrocentrics. In heterozygotes for chromosome 7, bivalents with a small buckle were observed in a small fraction of pachytene cells. No differences were found in the morphology and pairing pattern of sex bivalents, composed of the X and Y chromosomes derived from the same or different parental races. Univalents, multiv...Continue Reading

References

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Citations

Jan 19, 2013·Proceedings of the National Academy of Sciences of the United States of America·Tanmoy BhattacharyyaJiri Forejt
Mar 10, 2016·Asian-Australasian Journal of Animal Sciences·Xihe LiLixia Zhao
Jun 25, 2002·Biology of Reproduction·Elizabeth S NevesLuiz R França

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