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Chromosome-specific segmentation revealed by structural analysis of individually isolated chromosomes

Genes, Chromosomes & Cancer

Feb 15, 2011

Kunio KitadaS Aikawa

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Abstract

Analysis of structural rearrangements at the individual chromosomal level is still technologically challenging. Here we optimized a chromosome isolation method using fluorescent marker-assisted laser-capture and laser-beam microdissection and applied it to structural analysis of two abe...read more

Mentioned in this Paper

Flow Cytometry
Fluorescent in Situ Hybridization
Biologic Segmentation
Abnormal Fragmented Structure
Array-Based Comparative Genomic Hybridization
DNA, Neoplasm
Fluorescent stain
Autosome Abnormalities
Sequencing
Massively-Parallel Sequencing
Paper Details
References
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  • Citations3
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  • References34
  • Citations3
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Chromosome-specific segmentation revealed by structural analysis of individually isolated chromosomes

Genes, Chromosomes & Cancer

Feb 15, 2011

Kunio KitadaS Aikawa

PMID: 21319258

DOI: 10.1002/gcc.20847

Abstract

Analysis of structural rearrangements at the individual chromosomal level is still technologically challenging. Here we optimized a chromosome isolation method using fluorescent marker-assisted laser-capture and laser-beam microdissection and applied it to structural analysis of two abe...read more

Mentioned in this Paper

Flow Cytometry
Fluorescent in Situ Hybridization
Biologic Segmentation
Abnormal Fragmented Structure
Array-Based Comparative Genomic Hybridization
DNA, Neoplasm
Fluorescent stain
Autosome Abnormalities
Sequencing
Massively-Parallel Sequencing

Feeds With Similar Papers

Comparative Sequencing

Inter/Intra-Species: Comparative Sequencing describes the sequencing techniques that compare between and within species genomes. Discover the latest research on comparative sequencing of inter/intra-species here.

Precision Oncology

Precision oncology is a new approach to cancer treatment, which utilizes the molecular profiling of each tumor to develop and tailor treatment strategies to each patient. The use of these biomarkers from tumors will help to predict those who will respond to specific treatments. Here is the latest research on precision oncology.

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Mapping of balanced chromosome translocation breakpoints to the basepair level from microdissected chromosomes

Journal of Cellular and Molecular MedicineJuly 6, 2010
Anna C ObenaufJochen B Geigl
Paper Details
References
  • References34
  • Citations3
1234
  • References34
  • Citations3
1

Download from

Publisher
PubMed
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