Sep 22, 2010

Chronic and regular use of statin prevents atrial fibrillation in period after cardiac surgery

Arquivos brasileiros de cardiologia
Renato Jorge AlvesKenji Nakiri

Abstract

[Corrected] Atrial fibrillation is a common complication after cardiac surgery. The previous use of statins may reduce the incidence of this arrhythmia. To evaluate whether the chronic and regular use of statins, for a period of six months, prevents atrial fibrillation after elective cardiac surgery. A study carried out with 107 patients that underwent cardiac surgery, including 66% of males and their mean age was 60.4 years (25 to 84). We evaluated the presence of atrial fibrillation among patients that used statins or not on a regular basis in the preoperative period. We excluded patients with urgent heart surgery, kidney failure, inflammatory diseases, previous atrial fibrillation, patients with thyroid disease and those using a permanent pacemaker. In the postoperative period, atrial fibrillation was present in 42 patients (39%) of the sample, including 11 (26%) people that had used statins on a regular basis in the preoperative period and 31 (74%) who had not. It was possible to observe that, in 22% of the patients that were using statin, there was no development of atrial fibrillation, while 45% of those who did not take statin had arrhythmia (ρ = 0.02). In the isolated myocardial revascularization, 47% of the patients th...Continue Reading

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Mentioned in this Paper

Kidney Failure
Discipline of Heart Surgery
Myocardium
Cardiac Surgery Procedures
Renal Insufficiency
Thyroid Diseases
Atrial Fibrillation
Complication
Myositis
Preoperative Procedure

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