Chronic Arsenic Poisoning Probably Caused by Arsenic-Based Pesticides: Findings from an Investigation Study of a Household

International Journal of Environmental Research and Public Health
Yongfang LiXinghua Gao

Abstract

In addition to naturally occurring arsenic, man-made arsenic-based compounds are other sources of arsenic exposure. In 2013, our group identified 12 suspected arsenicosis patients in a household (32 living members). Of them, eight members were diagnosed with skin cancer. Interestingly, all of these patients had lived in the household prior to 1989. An investigation revealed that approximately 2 tons of arsenic-based pesticides had been previously placed near a well that had supplied drinking water to the family from 1973 to 1989. The current arsenic level in the well water was 620 μg/L. No other high arsenic wells were found near the family's residence. Based on these findings, it is possible to infer that the skin lesions exhibited by these family members were caused by long-term exposure to well water contaminated with arsenic-based pesticides. Additionally, biochemical analysis showed that the individuals exposed to arsenic had higher levels of aspartate aminotransferase and γ-glutamyl transpeptidase than those who were not exposed. These findings might indicate the presence of liver dysfunction in the arsenic-exposed individuals. This report elucidates the effects of arsenical compounds on the occurrence of high levels of a...Continue Reading

References

Aug 15, 1992·American Journal of Epidemiology·J CuzickS Evans
Apr 19, 1973·The New England Journal of Medicine·E J Feinglass
Mar 10, 1984·Lancet·J CuzickP S Mortimer
Jun 1, 1982·British Journal of Cancer·J CuzickD A Price Evans
Jul 1, 1984·Archives of Environmental Health·C W ArmstrongG B Miller
Apr 1, 1994·American Journal of Industrial Medicine·B J Lagerkvist, B Zetterlund
Mar 26, 2002·Journal of Occupational and Environmental Medicine·Hiroto NakadairaMasaharu Yamamoto
May 1, 2004·American Journal of Public Health·Yu Chen, Habibul Ahsan
Apr 28, 2005·Journal of Agricultural and Food Chemistry·Min FengYong Cai
Jun 22, 2005·Toxicology and Applied Pharmacology·D N Guha Mazumder
Apr 28, 2006·Integrated Environmental Assessment and Management·Rupali Datta, Dibyendu Sarkar
Jun 30, 2006·Journal of Biomedical Science·Hsin-Su YuChee-Yin Chai
Jun 15, 2007·Journal of the National Cancer Institute·Guillermo MarshallAllan H Smith
Jun 21, 2008·Toxicological Sciences : an Official Journal of the Society of Toxicology·Jie Liu, Michael P Waalkes
Jul 22, 2008·Toxicology and Applied Pharmacology·Yuanyuan XuGuifan Sun
Jan 28, 2009·Indian Journal of Dermatology, Venereology and Leprology·Sujit Ranjan SenguptaPijush Kanti Datta
Jan 28, 2009·Indian Journal of Dermatology, Venereology and Leprology·Nilay Kanti Das, Sujit Ranjan Sengupta
Aug 21, 2010·The Annals of Occupational Hygiene·Donguk ParkDomyung Paek
May 18, 2011·American Journal of Epidemiology·Maria ArgosHabibul Ahsan
Apr 14, 2012·Journal of Gastroenterology and Hepatology·Won SohnHo Soon Choi
Nov 13, 2012·Journal of Hazardous Materials·Shahida QuaziRupali Datta
Mar 6, 2013·Environmental Health Perspectives·Marisa F NaujokasWilliam A Suk
Oct 18, 2013·Journal of Epidemiology and Community Health·Weijing WangDongfeng Zhang
Jun 12, 2014·International Journal of Hygiene and Environmental Health·Tamás RudnaiPéter Rudnai
Sep 30, 2014·Environmental Research·Weijing WangDongfeng Zhang
Jan 28, 2015·Environmental Health Perspectives·Reginald QuansahMawuli Dzodzomenyo

❮ Previous
Next ❯

Citations

Jul 3, 2016·Toxicological Sciences : an Official Journal of the Society of Toxicology·Xiaofan XuMichelle A Mendez
Nov 18, 2016·Environmental Monitoring and Assessment·Luigi VimercatiGiorgio Assennato
Jan 11, 2020·Indian Journal of Occupational and Environmental Medicine·Md Samiur RahmanSushil Kumar Singh
Mar 23, 2017·Environmental Science and Pollution Research International·Luigi VimercatiAntonio Baldassarre
Feb 22, 2021·The Science of the Total Environment·Yina ChenMinjian Chen

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsies
biopsy

Related Concepts

Related Feeds

Carcinoma, Basal Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Bowen's Disease

Bowen's disease is thought of as an easily-treatable early stage of skin cancer, characterized by red, scaly patches on the skin. Discover the latest research on Bowen's disease here.