PMID: 7027865Jan 1, 1981Paper

Chronic atrophic polychondritis and renal and cardiopulmonary amylosis: a case report and literature review (author's transl)

Annales de médecine interne
J LambrozoJ P Leclerc

Abstract

Glomerular lesions with a nephrotic syndrome and impaired renal function developed secondary to a chronic atrophic polychondritis confirmed by auricular biopsy. In the absence of renal histology data, the possibility of an iatrogenic complication or a renal lesion specific to the affection itself were successively eliminated. Pos-mortem histological examination demonstrated renal and cardiopulmonary amylosis, the latter being clinically asymptomatic. The probable autoimmune origin of the chronic atrophic polychondritis has to be discussed in parallel with the dysimmunity mechanism responsible for the amyloid lesions, but no relationship between them was demonstrated.

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