Chronic cadmium exposure and cardiovascular disease in adults

Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
Emmanuel Obeng-Gyasi

Abstract

Chronic cadmium exposure and its effect on cardiovascular-related markers were explored in the cross-sectional study of U.S. adults using the National Health and Nutrition Examination Survey (NHANES) 2007-2010 data. Cardiovascular-related markers, such as LDL cholesterol mg/dL (LDL-C), non-HDL cholesterol mg/dL (non-HDL-C), triglycerides mg/dL (TG), c-reactive protein mg/dL (CRP), and gamma-glutamyl transferase U/L (GGT) were explored in relation to urine cadmium level µg/L (UCL). The variables and their relation to UCL µg/L were explored both as continuous and categorical variables using linear and logistic regression models and basic descriptive statistics. Geometric Mean values of the markers of interest were statistically significantly more elevated in middle-aged adults (45-65 years) as compared to younger adults (18-44 years). In linear regression analysis, CRP mg/dL, LDL-C mg/dL, non-HDL-C mg/dL, and GGT U/L levels were significantly associated with UCLs mg/dL after adjusting for confounding variables. In binary logistic regression models, young and middle-aged adults chronically exposed to cadmium were significantly more likely to have elevated CRP mg/dL levels. This study suggests that chronic exposure to cadmium alter...Continue Reading

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Citations

Apr 4, 2021·International Journal of Environmental Research and Public Health·Meghan A CookSamuel Collins
Jul 3, 2021·International Journal of Environmental Research and Public Health·Emmanuel Obeng-GyasiMichael A Province
Aug 8, 2021·International Journal of Environmental Research and Public Health·Anatoly V SkalnyAlexey A Tinkov
Aug 28, 2021·International Journal of Environmental Research and Public Health·Patricia RojasAldo A Reséndiz-Albor

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