Chronic carbon disulfide encephalopathy

European Neurology
C C HuangT S Shih

Abstract

To understand central nervous damage after long-term exposure to carbon disulfide (CS2), 10 patients who had polyneuropathy with various neuropsychiatric symptoms in a viscose rayon plant were studied. Clinical and laboratory examinations including electroencephalography (EEG), brain computed tomography (CT), brain magnetic resonance images (MRI), and carotid duplex sonography were carried out. Clinically, headache, unpleasant dreams, memory impairment, fatigue, anorexia and emotional lability were common in these patients while 2 patients had stroke episodes. EEGs were all normal. Brain CT scan showed mild cortical atrophy in 3 and low density lesions in the basal ganglia in 3. Brain MRI studies also disclosed mild cortical atrophy in 4 and multiple lesions involving the basal ganglia and corona radiata in 4. Carotid duplex sonography revealed mild atherosclerosis with plaques (< 20% stenosis) of extracranial vessels in 6. However there was no significant difference in flow velocities and flow volumes in the extracranial carotid arteries between patients and the normal controls. Interestingly, 2 patients had multiple brain lesions in the subcortical white matter but without strokes. In conclusion, encephalopathy with possible ...Continue Reading

Citations

Aug 29, 1998·Environmental Health Perspectives·H Frumkin
Jul 23, 2011·The International Journal of Neuroscience·Ning DingZhenzhong Li
Dec 7, 2006·Neurotoxicology·Wen-Li ChuangTung-Sheng Shih
Mar 1, 2006·International Journal of Hygiene and Environmental Health·Lode GodderisMineke Viaene
Nov 10, 2000·Primary Care·R J Harrison
Mar 11, 2005·Neurologic Clinics·Tracy Eicher, Eleanor Avery
Nov 3, 2017·Annals of Occupational and Environmental Medicine·Hweemin ChungKyunggeun Park
Sep 25, 2002·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Joo Hee ChaMi Jung Kim
Oct 10, 2002·Acta Neurologica Scandinavica·S K ChoM A Son

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