Chronic diarrhea among adults in Kigali, Rwanda: association with bacterial enteropathogens, rectocolonic inflammation, and human immunodeficiency virus infection

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
J ClerinxP Van de Perre

Abstract

One hundred patients with chronic diarrhea were seen in the Department of Internal Medicine at the Centre Hospitalier de Kigali, Rwanda; stool and/or rectal swab culture was performed for these patients, and they underwent rectoscopy and serological testing for human immunodeficiency virus type 1 (HIV-1). Enteropathogenic bacteria were isolated from 39 (39%) of the patients: Shigella species (22 of 100 patients tested), non-typhi Salmonella (11/100), Aeromonas species (5/60), and Campylobacter species (4/60). Rectocolitis was seen in 70 (70%) of the patients. HIV-1 antibodies were detected in 82 (94%) of 87 patients tested. Cytomegalovirus was not found in rectal biopsy specimens from 29 patients. Entamoeba histolytica was detected in two of 31 rectal smears. Idiopathic ulcerative colitis was diagnosed for two HIV-1-seropositive patients. One or more AIDS-defining diseases were found in 32 (32%) of the patients, and 72 (72%) fulfilled the World Health Organization's clinical case definition criteria for AIDS. Chronic diarrhea, as seen in a hospital setting in a region highly endemic for HIV-1 infection, is strongly associated with HIV-1 infection, with rectocolonic inflammation, and with infection due to enteropathogenic bacteria.

Citations

Aug 17, 2004·Transactions of the Royal Society of Tropical Medicine and Hygiene·Paul KellyAlan Phillips
Jul 5, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M S DworkinUNKNOWN Adult and Adolescent Spectrum of HIV Disease Project
Mar 29, 2002·AIDS·Xavier AnglaretUNKNOWN ANRS 059-Cotrimo-CI study group
Aug 25, 2007·Journal of Gastroenterology and Hepatology·David J HolthouseLivinia Hallam
Jan 22, 2002·Akusherstvo i ginekologii︠a︡·V PorozhanovaV Khristova
Jul 11, 1998·Infectious Disease Clinics of North America·M D Mileno, F J Bia
Sep 30, 2016·African Journal of AIDS Research : AJAR·Charlotte G NeumannJudith A Ernst
Apr 25, 2009·Revista Do Instituto De Medicina Tropical De São Paulo·Andréa Regina Baptista RossitRicardo Luiz Dantas Machado
Jun 11, 2004·Médecine sciences : M/S·Xavier Anglaret, Roger Salamon
Feb 22, 2001·Journal of Travel Medicine·H J KoornhofL McGee

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