Chronic ergotamine abuse: evidence of functional impairment of long ascending spinal tracts

European Neurology
A C LudolphG G Brune

Abstract

22 migraine patients with a history of chronic ergotamine abuse were compared with 12 patients with a similar intake of dihydroergotamine. The study of somatosensory-evoked potentials showed that 50% of the patients with a history of ergotamine abuse had increased central conduction times after stimulation of the tibial nerve. Corticomotoneuronal latencies obtained by noninvasive electrical stimulation of the motor cortex were normal in 5 patients. The functional sensory deficits were not related to clinical impairment and were more frequently observed in patients with a comparatively high mean daily and cumulative intake.

Citations

May 8, 2008·Cephalalgia : an International Journal of Headache·P C Tfelt-Hansen, P J Koehler
Oct 1, 2010·Internal and Emergency Medicine·Pierangelo GeppettiSilvia Benemei
Sep 25, 2007·Cephalalgia : an International Journal of Headache·A M RhodeS Evers
Feb 1, 1996·Cephalalgia : an International Journal of Headache·W J Meyler
May 25, 2005·Cephalalgia : an International Journal of Headache·S D SilbersteinUNKNOWN International Headache Society
Oct 1, 1995·Cephalalgia : an International Journal of Headache·M WilkinsonT J Steiner

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