Abstract
Results of a number of investigations indicate attention is a multifactorial construct composed of four distinct cognitive factors including focus-execute, sustain, encode and shift abilities. While investigators have partially or fully replicated this attentional structure in a number of clinical and nonclinical populations, no study has adequately examined the structure of attention in patients with schizophrenia who are not treated with antipsychotics. In this study, we examined the four-factor theory of attention in patients with schizophrenia while they were stabilized on haloperidol (with no adjunctive antiparkinsonian/anticholinergic medications) and again when they were approximately 3 weeks drug free. Standard neuropsychological measures were used to assess attentional functions. Principal components analyses (varimax rotation) of neuropsychological test scores in medicated and drug-free conditions indicated that four factors accounted for 84.2 and 91.8 of total variance in medicated and unmedicated conditions, respectively. Based on these results, it appears that: (1) haloperidol does not appreciably affect structure of the attentional system in patients with schizophrenia; (2) unmedicated patients with schizophrenia ...Continue Reading
References
Feb 1, 1992·The Journal of Nervous and Mental Disease·W S KremenM T Tsuang
Jun 1, 1991·Neuropsychology Review·A F MirskyS G Kellam
Dec 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·D J King
Jan 1, 1991·Psychiatry Research·K S KendlerA F Mirsky
Oct 1, 1990·Schizophrenia Research·P G NestorS F Sands
Jan 1, 1989·Neuropsychologia·A G CanavanC E Polkey
Oct 1, 1987·Environmental Health Perspectives·A F Mirsky
Aug 1, 1987·Journal of Clinical and Experimental Neuropsychology·G J Larrabee
Mar 1, 1974·Clinical Obstetrics and Gynecology·D R Mishell
Apr 7, 1965·Psychopharmacologia·G A Talland, G C Quarton
Jan 1, 1984·Schizophrenia Bulletin·K H Nuechterlein, M E Dawson
Jun 1, 1995·Journal of Neurology, Neurosurgery, and Psychiatry·L Cipolotti, E K Warrington
Jun 1, 1994·Journal of Clinical and Experimental Neuropsychology·D L PoggeP D Harvey
Jul 1, 1993·Journal of Clinical and Experimental Neuropsychology·K Perrine
Oct 1, 1956·Journal of Consulting Psychology·L H BECKI SARASON
Sep 1, 1963·Archives of General Psychiatry·W E BUNNEY, D A HAMBURG
Jan 1, 1988·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·A MedaliaA Merriam
Citations
Jun 1, 2005·Schizophrenia Research·Jejoong KimSohee Park
Feb 6, 2004·Journal of Psychiatric Research·Michelle W C ChanTatia M C Lee
Feb 12, 2009·Applied Neuropsychology·Brandon S ParkJoan Mayfield
Mar 4, 2010·Journal of Clinical and Experimental Neuropsychology·Lisa A DukeJason Schwartz
Apr 20, 2010·Journal of Clinical and Experimental Neuropsychology·Nicholas S ThalerJoan Mayfield
Oct 28, 2009·The Clinical Neuropsychologist·Nicholas S ThalerJoan Mayfield
Sep 10, 2011·The Clinical Neuropsychologist·Sally J BarneyJoan Mayfield
Nov 13, 2007·Depression and Anxiety·Jejoong KimJun Soo Kwon
Nov 18, 2005·Brain Research. Cognitive Brain Research·C SchmiedtC Basar-Eroglu
Dec 4, 1998·Assessment·D N AllenD P van Kammen
Nov 25, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Lucas Lecourtier, Peter H Kelly
Apr 22, 2019·The Cochrane Database of Systematic Reviews·Adib EssaliNawar AlMounayer