Chronic heart failure: contemporary diagnosis and management.

Mayo Clinic Proceedings
Gautam V RamaniMandeep R Mehra

Abstract

Chronic heart failure (CHF) remains the only cardiovascular disease with an increasing hospitalization burden and an ongoing drain on health care expenditures. The prevalence of CHF increases with advancing life span, with diastolic heart failure predominating in the elderly population. Primary prevention of coronary artery disease and risk factor management via aggressive blood pressure control are central in preventing new occurrences of left ventricular dysfunction. Optimal therapy for CHF involves identification and correction of potentially reversible precipitants, target-dose titration of medical therapy, and management of hospitalizations for decompensation. The etiological phenotype, absolute decrease in left ventricular ejection fraction and a widening of QRS duration on electrocardiography, is commonly used to identify patients at increased risk of progression of heart failure and sudden death who may benefit from prophylactic implantable cardioverter-defibrillator placement with or without cardiac resynchronization therapy. Patients who transition to advanced stages of disease despite optimal traditional medical and device therapy may be candidates for hemodynamically directed approaches such as a left ventricular as...Continue Reading

References

Nov 1, 1991·Circulation·M Gheorghiade, D Ferguson
May 1, 1991·The American Journal of Cardiology·J K GhaliY L Liao
Aug 1, 1991·The New England Journal of Medicine·UNKNOWN SOLVD InvestigatorsJay N Cohn
Feb 10, 1989·JAMA : the Journal of the American Medical Association·L W Stevenson, J K Perloff
Mar 1, 1985·Annals of Internal Medicine·M R VaskoD C Brater
May 1, 1970·Circulation·M J BuckleyW G Austen
Dec 23, 1971·The New England Journal of Medicine·P A McKeeW B Kannel
Jul 22, 1982·The New England Journal of Medicine·M R BristowE B Stinson
Jun 1, 1995·Journal of the American College of Cardiology·K YamamotoK Shimada
May 1, 1995·Hypertension·M W GillmanC H Hennekens
Oct 1, 1993·Journal of the American College of Cardiology·K K HoD Levy
May 22, 1996·JAMA : the Journal of the American Medical Association·D LevyK K Ho
Feb 20, 1997·The New England Journal of Medicine·UNKNOWN Digitalis Investigation Group
Jul 30, 1999·American Heart Journal·M S WeinfeldL W Stevenson
May 12, 2000·Journal of the American College of Cardiology·J S GottdienerR C Boineau
Jun 2, 2001·The New England Journal of Medicine·M PackerUNKNOWN Carvedilol Prospective Randomized Cumulative Survival Study Group
Jun 2, 2001·The New England Journal of Medicine·UNKNOWN Beta-Blocker Evaluation of Survival Trial InvestigatorsPhilip W Lavori

❮ Previous
Next ❯

Citations

Sep 15, 2010·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Yalena Amador-Cañizares, Santiago Dueñas-Carrera
Feb 7, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Juanhui PeiJielin Pu
May 24, 2011·Vascular Health and Risk Management·Pablo Pazos-LópezAlfonso Castro-Beiras
Oct 21, 2010·The Physician and Sportsmedicine·Heather PadillaLuc Djoussé
Sep 4, 2010·Expert Opinion on Investigational Drugs·Graziano RiccioniNicolantonio d'Orazio
May 24, 2011·International Journal of Nephrology·Adam RomanovskyMitchell H Rosner
Jan 8, 2016·Journal of Molecular and Cellular Cardiology·Akihiko KubotaYoshio Kobayashi
Jun 5, 2013·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Marta Inês Martins da SilvaAna Paula Morão Moreira
Oct 29, 2015·European Journal of Heart Failure·Berhe W SahleUNKNOWN Second Australian National Blood Pressure Study Management Committee
Jun 9, 2012·Mayo Clinic Proceedings·Muaz M AbudiabWilliam K Freeman
Aug 9, 2011·Revista española de cardiología·Jovan KuzmicicSergio Lavandero
Jun 2, 2011·Primary Care·Sandhya Murthy, Hannah I Lipman
May 24, 2011·The Canadian Journal of Cardiology·Kleopatra RaptiRoger J Hajjar
Oct 13, 2010·Journal of Molecular and Cellular Cardiology·Qinghang Liu, Jeffery D Molkentin
Jul 2, 2010·Mayo Clinic Proceedings·J Timothy Hanlon
Apr 8, 2016·ASEAN Heart Journal : Official Journal of the ASEAN Federation of Cardiology·Ramon F AbarquezElleen L Cunanan
May 23, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Song Wen-TingLiu Jian-Xun
Aug 3, 2011·Clinical and Experimental Pharmacology & Physiology·Luisa R de MeirellesTatiana M C Brunini
May 28, 2011·European Journal of Clinical Investigation·Gianluca TestaPasquale Abete
Nov 5, 2014·International Journal of Clinical Practice·D SauraG de la Morena
Apr 2, 2014·Mayo Clinic Proceedings·Shannon M DunlaySudhir S Kushwaha
Apr 29, 2011·The Annals of Thoracic Surgery·Giuseppe SpezialeLuigi Tavazzi
Feb 8, 2011·The American Journal of Cardiology·Gaetano SantulliGuido Iaccarino
Apr 9, 2015·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Dongfang WangJoseph B Zwischenberger
Jun 13, 2015·Nature Communications·Changwon KhoRoger J Hajjar
Jun 7, 2011·International Journal of Cardiology·Danish AliPrithwish Banerjee
May 15, 2013·International Journal of Cardiology·Laszlo LittmannSarah L Marconi
Apr 27, 2016·Heart Failure Reviews·Patrick Asare FordjourGuanwei Fan
Jun 30, 2016·Proceedings of the National Academy of Sciences of the United States of America·Richard CarrJeffrey L Benovic
Oct 19, 2016·The Journal of Cardiovascular Nursing·Sami Y Al-RawashdehMisook L Chung
Oct 26, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Seema Patel
Nov 1, 2016·Expert Review of Cardiovascular Therapy·Hani N Sabbah
Apr 4, 2017·International Heart Journal·Zhang PingShao Liang
May 28, 2011·Journal of Intensive Care Medicine·Paul E Marik, Mark Flemmer
Jan 23, 2018·Future Cardiology·Bruno BordoniBeatrice Sacconi
May 23, 2014·Circulation. Heart Failure·Nina Ghosh, Raymond Y Kwong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Antianginal Drugs: Mechanisms of Action

Antianginal drugs, including nitrates, beta-blockers, and calcium channel blockers, are used in the treatment of angina pectoris. Here is the latest research on their use and their mechanism of action.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.