Chronic Hepatitis E in Rheumatology and Internal Medicine Patients: A Retrospective Multicenter European Cohort Study

Viruses
Sven PischkeVincent Mallet

Abstract

Objectives: Hepatitis E virus (HEV) infection is a pandemic with regional outbreaks, including in industrialized countries. HEV infection is usually self-limiting but can progress to chronic hepatitis E in transplant recipients and HIV-infected patients. Whether other immunocompromised hosts, including rheumatology and internal medicine patients, are at risk of developing chronic HEV infection is unclear. Methods: We conducted a retrospective European multicenter cohort study involving 21 rheumatology and internal medicine patients with HEV infection between April 2014 and April 2016. The underlying diseases included rheumatoid arthritis (n = 5), psoriatic arthritis (n = 4), other variants of chronic arthritis (n = 4), primary immunodeficiency (n = 3), systemic granulomatosis (n = 2), lupus erythematosus (n = 1), Erdheim⁻Chester disease (n = 1), and retroperitoneal fibrosis (n = 1). Results: HEV infection lasting longer than 3 months was observed in seven (33%) patients, including two (40%) patients with rheumatoid arthritis, three (100%) patients with primary immunodeficiency, one (100%) patient with retroperitoneal fibrosis and one (100%) patient with systemic granulomatosis. Patients with HEV infection lasting longer than 3 ...Continue Reading

References

Feb 22, 2008·The New England Journal of Medicine·Nassim KamarLionel Rostaing
Feb 22, 2008·The New England Journal of Medicine·René GérolamiPhilippe Colson
Sep 4, 2009·The New England Journal of Medicine·Harry R DaltonSamreen Ijaz
Oct 30, 2009·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Sven PischkeHeiner Wedemeyer
Oct 19, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Pothakamuri Venkata SuneethaHeiner Wedemeyer
Apr 28, 2012·Gastroenterology·Heiner WedemeyerMichael P Manns
Mar 16, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Sven PischkeHeiner Wedemeyer
Apr 9, 2013·Seminars in Liver Disease·H R DaltonR Bendall
May 11, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·N KamarJ Izopet
Jan 1, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Christoph Höner zu SiederdissenHeiner Wedemeyer
Mar 22, 2014·The New England Journal of Medicine·Nassim KamarVincent Mallet
Apr 11, 2015·Medicine·Hélène BauerUNKNOWN Club Rhumatismes et Inflammation, a section of the French Society of Rheumatology
Jun 23, 2015·Transplant Infectious Disease : an Official Journal of the Transplantation Society·A GalanteM Sterneck
Mar 24, 2016·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jean Michel MansuyJacques Izopet
Apr 9, 2016·Clinics and Research in Hepatology and Gastroenterology·P IngilizS Pischke
Dec 4, 2016·Journal of Hepatology·Sven PischkeAnnemiek A Van der Eijk
Mar 30, 2017·Clinical Journal of Gastroenterology·Kazuyuki SuzukiHiroaki Okamoto
Jun 21, 2017·Proceedings of the National Academy of Sciences of the United States of America·Dianjun CaoXiang-Jin Meng
Apr 4, 2018·Journal of Hepatology·UNKNOWN European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu, UNKNOWN European Association for the Study of the Liver
Aug 31, 2018·Oxford Medical Case Reports·Anne E M RobinsWilliam T H Gelson

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Citations

Jun 21, 2019·Viruses·Laura CorneilliePhilip Meuleman
Jan 30, 2020·Journal of Clinical Medicine·Sébastien LhommeNassim Kamar
Jul 10, 2019·Viruses·Thomas HorvatitsSven Pischke
Sep 26, 2020·BMC Rheumatology·Salvatore Di BartolomeoPaola Cipriani
Oct 20, 2020·World Journal of Gastroenterology : WJG·Abdullah Tarık Aslan, Hatice Yasemin Balaban
Dec 11, 2020·Journal of Viral Hepatitis·Myrte GorrisJoep de Bruijne
Oct 10, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Gustav BuescherThomas Horvatits
Apr 7, 2020·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·G W Webb, H R Dalton
Feb 24, 2021·Journal of Clinical Immunology·Prebashan MoodleyAshwin Dhanda
May 12, 2021·Liver International : Official Journal of the International Association for the Study of the Liver·Hélène LarrueJean-Marie Peron
Mar 23, 2020·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Elisa FurfaroMalgorzata Mikulska

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Methods Mentioned

BETA
PCR
nucleic acid amplification
genotyping

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