PMID: 6975827Sep 1, 1981Paper

Chronic interstitial cystitis as an initial major manifestation of systemic lupus erythematosus

The Journal of Rheumatology
A R de la Serna, D Alarcon-Segovia

Abstract

Chronic interstitial cystitis (CIC) has been thought to result from autoimmune phenomena and its occurrence in systemic lupus erythematosus (SLE) has occasionally been recorded. We report a patient with SLE whose initial urinary symptoms were caused by CIC. Two of 3 patients (including ours) whose cases have been reported also had diarrhea, a common symptom in idiopathic CIC. All 3 patients had cutaneous and/or bladder vasculitis. CIC occurring in SLE seems to be due to immune complex deposition.

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