Abstract
Although chronic kidney disease (CKD) is a risk factor for cardiovascular disease, information about myocardial infarction (MI) with CKD is limited in the acute revascularization era. To clarify the relationship between CKD and long-term outcomes of MI, consecutive 4550 patients with acute MI treated at 17 participating hospitals were analyzed. The primary study outcome was death from any cause, and a secondary endpoint was the first appearance major adverse cardiovascular events. Acute revascularization therapies were performed in 75.2% of the patients and the mean left ventricular ejection fraction (LVEF) was 53%. The median follow-up was 4.1 years (follow-up rate, 95.2%). Patients were divided into four categories (<45.0, 45.0 to 59.9, 60.0 to 74.9, and ≥ 75.0 mL/min per 1.73 m(2) of body-surface area) according to the glomerular filtration rate (GFR) estimated by the Modification of Diet in Renal Disease equation. A total of 1941 (42.7%) patients had an estimated GFR of <60.0 mL/min per 1.73 m(2). Mortality rates increased with declining estimated GFR. Unadjusted hazard ratios for total and cardiovascular death in the group with an estimated GFR of 45.0 to 59.9 mL/min per 1.73 m(2) using the group with an estimated GFR of ≥...Continue Reading
References
Sep 17, 1998·The New England Journal of Medicine·C A HerzogA J Collins
Sep 7, 2000·European Heart Journal
Sep 22, 2001·The New England Journal of Medicine·B M BrennerUNKNOWN RENAAL Study Investigators
Oct 3, 2002·Circulation·Eugene BraunwaldUNKNOWN American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of
Oct 29, 2003·Circulation·Mark J SarnakUNKNOWN American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology,
Nov 12, 2003·The New England Journal of Medicine·Marc A PfefferUNKNOWN Valsartan in Acute Myocardial Infarction Trial Investigators
Apr 29, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·UNKNOWN Kidney Disease Outcomes Quality Initiative (K/DOQI)
Sep 24, 2004·The New England Journal of Medicine·Alan S GoChi-yuan Hsu
Oct 2, 2004·Kidney International·Garabed EknoyanHaiyan Wang
Dec 22, 2004·Annals of Internal Medicine·Andrew D RuleFernando G Cosio
May 11, 2005·Kidney International·Andrew S LeveyGarabed Eknoyan
Sep 20, 2005·American Heart Journal·Hiroshi KasanukiUNKNOWN HIJAMI Investigators
Mar 1, 2006·American Heart Journal·François SchieleJean-Pierre Bassand
Jun 9, 2006·The New England Journal of Medicine·Lesley A StevensAndrew S Levey
Sep 22, 2006·Journal of the American Society of Nephrology : JASN·Ying-Chun MaHai-Yan Wang
Mar 27, 2007·Clinical and Experimental Nephrology·Enyu ImaiSeiichi Matsuo
Apr 25, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Liam G GlynnAndrew W Murphy
Dec 12, 2007·Circulation·Elliott M AntmanClyde W Yancy
Mar 16, 2011·International Journal of Cardiology·Narumi OkuraNobuhisa Hagiwara
Citations
Jul 12, 2013·Current Cardiology Reports·Usman Baber, Uschi Auguste
Jan 18, 2018·Heart and Vessels·Naoyuki AkashiHideo Fujita
Sep 2, 2020·Journal of Nephrology·Giacomo DeferrariEdoardo La Porta
Jun 29, 2021·IJC Heart & Vasculature·Mark CoyleCatriona Jennings