Chronic kidney disease in adults with schizophrenia: A nationwide population-based study

General Hospital Psychiatry
Dana Tzur BitanArnon D Cohen

Abstract

Several studies have recently reported an association between chronic kidney disease (CKD) and schizophrenia, yet this association has not been sufficiently established. The aim of this study was to examine the association between schizophrenia and CKD in a large dataset, as well as to assess the level of accessibility of these patients to common treatments for CKD. Patients diagnosed with schizophrenia (n = 27,516) and an equal number of age and sex frequency-matched controls were included in this nationwide population-based study. Logistic regressions and ROC curves were employed to assess the association between schizophrenia and CKD and the level of fit of the models. Schizophrenia was associated with CKD, after controlling for demographic, behavioral, and medical risk factors (OR = 1.62, CI 1.45-1.82, p < .0001). After adjusting for demographic and behavioral risk factors, CKD patients without schizophrenia were more likely to receive dialysis (OR = 1.70, 95% CI 1.18-2.44, p < .01) and kidney transplantation (OR = 5.43, 95% CI 2.84-10.38, p < .001) as compared to CKD patients with schizophrenia. As CKD affects survival, quality of life, and medical and familial burden, additional thought should be given to detection of CKD...Continue Reading

Citations

May 6, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·Dana Tzur BitanDaniel Feingold
Apr 20, 2021·Journal of Psychiatric Research·Israel KriegerDana Tzur Bitan
May 19, 2021·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Dana Tzur Bitan
Jun 10, 2021·Brain, Behavior, and Immunity·Michael D E SewellStephen M Lawrie
Jan 8, 2020·Dermatology : International Journal for Clinical and Investigative Dermatology·Dana Tzur BitanArnon Cohen
Sep 8, 2021·Asia-Pacific Journal of Public Health·Asnawi AbdullahMarthoenis Marthoenis

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