Chronic Lymphocytic Leukaemia/ Small-Cell Lymphocytic Lymphoma of the Lacrimal Sac: A Case Series

Ocular Oncology and Pathology
Yamini KrishnaSarah E Coupland

Abstract

Lymphomas of the lacrimal sac are rare, accounting for less than 10% of lacrimal sac malignant tumours. They may present with symptoms typical of secondary acquired nasolacrimal duct obstruction and are thus often misdiagnosed. Case series and literature review. Herein we describe 3 cases of chronic lymphocytic leukaemia (CLL)/small-cell lymphocytic lymphoma (SLL) of the lacrimal sac with immunohistochemical and in 1 case molecular confirmation. Lymphomas of the lacrimal sac should be suspected in patients with known CLL presenting with epiphora and dacryocystitis. During dacryocystorhinostomy, an incisional biopsy of the lacrimal sac is essential for confirming CLL/SLL involvement and may guide treatment.

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Citations

Apr 12, 2017·Asia-Pacific Journal of Ophthalmology·Yamini Krishna, Sarah E Coupland
Jul 17, 2021·Ophthalmic Plastic and Reconstructive Surgery·Vamsee K NeerukondaNatalie Wolkow

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