PMID: 6982616Sep 1, 1982Paper

Chronic lymphocytic leukemia: a monoclonal disease

American Journal of Hematology
D L SolankiR P MacDermott

Abstract

A black woman with chronic lymphocytic leukemia (CLL) was found to have monoclonal B lymphocytes with one type of surface immunoglobulin and one variant of G6PD (glucose-6-phosphate dehydrogenase) (G6PD A). Erythrocytes and T cells contained both G6PD A and G6PD B and hence were of polyclonal origin. The CLL cells in this patient likely arose from a developmental stage later than the step of differentiation into T and B lymphocytes. Furthermore, her erythrocytes did not arise from a stem cell affected by the CLL process.

References

Jan 1, 1979·Annual Review of Medicine·P J Fialkow
Oct 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·P J FialkowA Yoshida
Jan 15, 1962·Proceedings of the National Academy of Sciences of the United States of America·E BEUTLERV F FAIRBANKS

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Citations

Dec 1, 1991·Critical Reviews in Oncology/hematology·L VaickusK A Foon
Aug 1, 1993·American Journal of Hematology·Z M SthoegerA Berrebi
Jan 1, 1990·Medical Oncology and Tumor Pharmacotherapy·S KarfaJ S Nadkarni

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