Chronic meningococcaemia and immunoglobulin A deficiency

Journal of Medical Microbiology
Arnaud TheulinJean-Christophe Weber

Abstract

Chronic meningococcaemia is an unusual clinical presentation of Neisseria meningitidis infection. We describe the case of a patient, who presented with total IgA deficiency and partial IgM deficiency with a low switched memory B cells count, suggestive of a borderline form of common variable immunodeficiency (CVID). The role of IgA in the protection against Neisseria meningitidis, and the link between IgA deficiency and CVID are discussed.

References

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Citations

Apr 5, 2011·The Journal of Infection·Matthijs C BrouwerArie van der Ende
Mar 31, 2016·International Journal of Molecular Sciences·Sofia TorreggianiSusanna Esposito

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