PMID: 9443521Jan 1, 1997Paper

Chronic mild stress-induced reductions in saccharin intake depend upon feeding status

Journal of Psychopharmacology
J P HatcherJ J Hagan

Abstract

The consumption of a weak saccharin solution was examined in rats subjected to chronic mild stress (CMS). Intake of saccharin was reduced in stressed animals compared to isolated and group control animals but saccharin preference was not affected. Removal of water deprivation from the CMS schedule did not alter the effects of CMS upon saccharin intake. However, when food deprivation was omitted entirely from the CMS schedule the reduction in saccharin intake was eliminated. Similarly, in animals habituated to the full CMS procedure, reduction in saccharin intake was abolished by omitting food deprivation or by delaying the intake test for 24 h. Both CMS and food deprivation reduced water intake but had no effect on food consumed during the fluid-intake test. The presence of food deprivation during CMS appears to be a key factor affecting saccharin intake. Our data suggest that saccharin intake is not an appropriate measure of stress and anhedonia.

References

Jan 1, 1992·Neuroscience and Biobehavioral Reviews·R Muscat, P Willner
Jan 1, 1992·Neuroscience and Biobehavioral Reviews·P WillnerM Papp
Mar 1, 1992·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·J L MoreauW E Haefely
Aug 1, 1990·Biological Psychiatry·R MuscatP Willner
Jun 1, 1982·Pharmacology, Biochemistry, and Behavior·R J Katz
Jan 25, 1996·European Journal of Pharmacology·M PappP Willner
Dec 1, 1996·Physiology & Behavior·N F ForbesI C Reid

❮ Previous
Next ❯

Citations

May 7, 2005·Neuroscience and Biobehavioral Reviews·Rick A Bevins, Joyce Besheer
Jun 1, 2005·Neuroscience and Biobehavioral Reviews·Fritz A Henn, Barbara Vollmayr
Mar 23, 2004·Behavioural Brain Research·Janne GrønliReidun Ursin
Dec 14, 2002·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Riina HäidkindJaanus Harro
Dec 9, 2003·Stress : the International Journal on the Biology of Stress·C BielajewG Fouriezos
Mar 10, 2016·Neuroscience and Biobehavioral Reviews·Sakina J RizviSidney H Kennedy
Sep 11, 2007·Progress in Neuro-psychopharmacology & Biological Psychiatry·Margus TõnissaarJaanus Harro
Aug 28, 2015·Physiology & Behavior·Jaime FigueroaDominic Michael Dwyer
May 21, 2005·Behavioural Brain Research·Stathis BekrisZeta Papadopoulou-Daifoti
Jan 5, 2013·Pharmacology, Biochemistry, and Behavior·Christina A Wilson, Alvin V Terry
Dec 3, 2014·Neuroscience and Biobehavioral Reviews·Elizabeth J CroftonThomas A Green
May 29, 2012·Pharmacology, Biochemistry, and Behavior·Felicity M DalyLianne J Woodward
Apr 24, 2017·Physiology & Behavior·Samantha R SpierlingEric P Zorrilla

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.