Chronic obstructive pulmonary disease and acute myocardial infarction: effects on presentation, management, and outcomes

European Heart Journal. Quality of Care & Clinical Outcomes
Kieran J Rothnie, Jennifer K Quint

Abstract

Cardiovascular disease is a common cause of death in patients with chronic obstructive pulmonary disease (COPD) and is a key target for improving outcomes. However, there are concerns that patients with COPD may not have enjoyed the same mortality reductions from acute myocardial infarction (AMI) in recent decades as the general population. This has raised questions about differences in presentation, management and outcomes in COPD patients compared to non-COPD patients. The evidence points to an increased risk of death after AMI in patients with COPD, but it is unclear to what extent this is attributable to COPD itself or to modifiable factors including under-treatment with guideline-recommended interventions and drugs. We review the evidence for differences between COPD and non-COPD patients in terms of the presentation of AMI, its treatment, and outcomes both in hospital and in the longer term.

References

Jun 24, 2000·JAMA : the Journal of the American Medical Association·J G CantoC I Kiefe
Feb 22, 2007·Thorax·Lorcan P McGarveyUNKNOWN TORCH Clinical Endpoint Committee
Feb 24, 2007·The American Journal of Cardiology·Adam C SalisburyJohn A Spertus
May 30, 2007·Archives of Internal Medicine·Andrew T YanUNKNOWN Canadian Acute Coronary Syndromes 1 and 2 Registry Investigators
Jan 2, 2008·The European Respiratory Journal·L M FabbriK F Rabe
Dec 22, 2009·Chest·Gavin C DonaldsonJadwiga A Wedzicha
Jan 20, 2010·Journal of the American College of Cardiology·Yariv GerberUNKNOWN Israel Study Group on First Acute Myocardial Infarction
Mar 2, 2010·European Journal of Epidemiology·Cornelia SchneiderChristoph R Meier
Mar 23, 2010·PLoS Medicine·Peter J Barnes
Jun 19, 2010·The New England Journal of Medicine·Robert W YehAlan S Go
Jul 6, 2010·American Heart Journal·Francesca BursiVéronique L Roger
Dec 29, 2010·The American Journal of Medicine·David D McManusRobert J Goldberg
Feb 11, 2012·The European Respiratory Journal·David A McAllisterWilliam Macnee
Feb 2, 2013·Journal of the American College of Cardiology·Mark J EisenbergUNKNOWN ZESCA Investigators
Mar 6, 2013·Chest·John D Maclay, William MacNee
Jul 1, 2015·European Heart Journal. Quality of Care & Clinical Outcomes·Cornelia JunghansAdam Timmis
Nov 1, 2015·European Heart Journal. Quality of Care & Clinical Outcomes·Karam Sadoon AlzuhairiChristian Torp-Pedersen

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Citations

May 4, 2018·Journal of Clinical Pharmacology·Fayna Rodríguez-GonzálezAntonio Tugores
Jul 6, 2019·Thorax·Elizabeth SapeyJennifer K Quint
Jun 8, 2021·Heart & Lung : the Journal of Critical Care·Katherine M BreenHolli A DeVon

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BETA
pharmacotherapy

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