Chronic obstructive pulmonary disease

Lancet
Klaus F Rabe, Henrik Watz

Abstract

Chronic obstructive pulmonary disease (COPD) kills more than 3 million people worldwide every year. Despite progress in the treatment of symptoms and prevention of acute exacerbations, few advances have been made to ameliorate disease progression or affect mortality. A better understanding of the complex disease mechanisms resulting in COPD is needed. Smoking cessation programmes, increasing physical activity, and early detection and treatment of comorbidities are further key components to reduce the burden of the disease. However, without a global political and economic effort to reduce tobacco use, to regulate environmental exposure, and to find alternatives to the massive use of biomass fuel, COPD will remain a major health-care problem for decades to come.

Citations

Jul 31, 2018·European Journal of Preventive Cardiology·Teresa M Seccia, Lorenzo A Calò
Oct 3, 2018·Current Opinion in Pulmonary Medicine·Neeraj M Shah, Patrick B Murphy
Apr 22, 2018·The European Respiratory Journal·Jeanne-Marie PerotinValérian Dormoy
Nov 24, 2017·The European Respiratory Journal·Klaus F RabeLeonardo M Fabbri
Oct 28, 2017·The European Respiratory Journal·Henrik Watz
Feb 12, 2019·The American Journal of Gastroenterology·Søren S OlesenUNKNOWN Scandinavian Baltic Pancreatic Club
Apr 4, 2019·Thorax·John-Poul Ng-BlichfeldtMatthew Hind
Jul 2, 2019·Journal of the American Geriatrics Society·Kenichi MatsushitaMorimasa Takayama
Nov 1, 2017·MMW Fortschritte der Medizin·A GillissenMaria Paparoupa
Oct 12, 2019·International Journal of Environmental Research and Public Health·Avery AppersonArjun Mohan
Oct 5, 2019·Metabolites·Shama NazCraig E Wheelock
May 28, 2019·Neurology·Franziska HopfnerAnton Pottegård
Dec 14, 2019·The European Respiratory Journal·Benjamin WaschkiUNKNOWN German COSYCONET Cohort
Mar 7, 2020·Journal of Clinical Medicine·Judith BehnkeHarald Ehrhardt
Apr 5, 2020·Journal of Clinical Periodontology·Lewis WinningStefan Renvert
May 2, 2020·Biotechnology and Applied Biochemistry·Beibei SongHuiran Zhang
Mar 27, 2020·American Journal of Physiology. Lung Cellular and Molecular Physiology·Laura Florez-SampedroBarbro N Melgert
Jun 6, 2020·Critical Reviews in Toxicology·Stéphanie AlkoussaPerrine J Martin
Jan 23, 2018·Therapeutic Advances in Respiratory Disease·Ann D MorganJennifer K Quint
Jan 6, 2019·Pharmaceuticals·Joana NevesMartina U Muckenthaler
Jun 19, 2019·Nutrients·Egeria ScodittiDomenico Maurizio Toraldo

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