Chronic pouchitis after ileal pouch-anal anastomosis for ulcerative colitis: effect on quality of life.

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Matthias TurinaSusan Galandiuk

Abstract

Chronic pouchitis can be observed in up to 30% of patients after proctocolectomy with ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC). It remains a poorly understood complication and often requires chronic antibiotic and antidiarrheal treatment. We hypothesized that its occurrence can be predicted by distinct clinical parameters and that it adversely affects quality of life. Sixty-eight of 129 consecutive UC patients who underwent IPAA over a 10-year period were evaluated by Cleveland Clinic Global Quality of Life questionnaires, telephone interviews, and by chart review. Using bivariate comparison, clinical predictors for the occurrence of chronic pouchitis were sought, and postoperative data analyzed with regard to functional results and quality of life. Nineteen of 68 patients (28%) experienced chronic pouchitis, but its occurrence could not be predicted by any variable assessed. Patients with chronic pouchitis complained of more frequent fecal incontinence (32% vs. 4% in controls; P < 0.01), of more frequent bowel movements (7.7/day vs. 6.2/day; P < 0.05), and experienced severe abdominal pain more often (P < 0.05). Overall quality of life and satisfaction with surgery, as well as subjective health and energ...Continue Reading

References

Jul 8, 1978·British Medical Journal·A G Parks, R J Nicholls
Aug 1, 1995·Annals of Surgery·V W FazioT K Schroeder
Apr 29, 1998·Journal of Pediatric Gastroenterology and Nutrition·A G KaditisS R Targan
Feb 5, 1999·The Australian and New Zealand Journal of Surgery·P NeillyG L Hill
Jun 1, 2000·World Journal of Surgery·E J Simchuk, R C Thirlby
Jan 13, 2001·Diseases of the Colon and Rectum·G M EttorreP Valleur
Jun 8, 2001·Gastroenterology Clinics of North America·L Stocchi, J H Pemberton
Oct 8, 2003·Annals of Surgery·Victor W FazioConor P Delaney
Jan 13, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Jean-Paul AchkarVictor Fazio
Apr 30, 2005·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P P TekkisR J Nicholls

❮ Previous
Next ❯

Citations

Apr 8, 2014·World Journal of Gastroenterology : WJG·Jessica R Allegretti, Matthew J Hamilton
Oct 9, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Xian-Rui WuBo Shen
Apr 13, 2015·Journal of Pediatric Surgery·Stephanie F PolitesJohn H Pemberton
Feb 22, 2012·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·E HashaviaH Tulchinsky
Nov 8, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·U KarlbomL Påhlman
Jun 22, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·T BanasiewiczM Drews
Mar 19, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·K-K TanM J Solomon
Jun 20, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M WassermanT Osler
Apr 21, 2017·Inflammatory Bowel Diseases·Edward L BarnesMillie D Long
Jul 25, 2009·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Johanna HaapamäkiPerttu E T Arkkila
Feb 27, 2019·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Tahir K YozgatliDursun Bugra
Dec 29, 2013·International Journal of Colorectal Disease·Steffen KoerdtMichael S Kasparek
Dec 10, 2013·Diseases of the Colon and Rectum·Howard RossUNKNOWN Standards Practice Task Force of the American Society of Colon and Rectal Surgeons
May 16, 2017·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Jacqueline SammutJosianne Scerri
Jun 17, 2020·Journal of Pediatric Gastroenterology and Nutrition·Esther Orlanski-MeyerDan Turner
Aug 12, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Olga A LavrykScott R Steele
May 2, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Clément BresteauAntoine Meyer

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.