Chronic Spinal Cord Stimulation in the Treatment of Cerebral and Spinal Spasticity

Stereotactic and Functional Neurosurgery
A V DekopovEkaterina M Salova

Abstract

The aim of this investigation is to assess the effectiveness of spinal cord stimulation (SCS) in different groups of patients with spasticity of different origin. A retrospective study of the use of the method of SCS in 71 patients. The patient population was divided into two groups: 52 cerebral palsy (CP) cases and 19 patients diagnosed with spasticity caused by spinal injury. The mean age was 7.14 ± 4.06 and 35.68 ± 12.42 years, respectively. The CP group included 41 cases of paraparesis and 11 cases tetraparesis. One quadripolar electrode was implanted into the posterior epidural space at Th10-Th12 level and an implantable pulse generator (Itrel3, Medtronic) was placed in a standard fashion. We performed 3-5 stimulation sessions per day; each lasted 30 min. The stimulation parameters were as follows: rate 100-130 Hz, pulse width 120-300 ms, amplitude 1.5-4 V. The follow-up ranged from 2 to 9 years. Decrease in muscle tone was observed in all cases in the group of patients with spinal spasticity: from 3.71 ± 0.61 on the Ashworth scale before the operation to 2.26 ± 0.56 after the operation (p < 0.001). In the group of cerebral spasticity a significant decrease in muscle tone was observed only in patients with spastic lower pa...Continue Reading

Citations

Apr 4, 2017·Neuromodulation : Journal of the International Neuromodulation Society·Sean J NagelMatthew A Howard
Jan 9, 2017·Neuroscience Letters·I A SolopovaT R Moshonkina
Sep 26, 2020·Frontiers in Bioengineering and Biotechnology·Germana CappelliniYury Ivanenko
Oct 19, 2019·Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury·A A SavenkovaT R Moshonkina
Jul 11, 2021·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Parag GadV Reggie Edgerton

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