Chronic spontaneous urticaria: an autoimmune disease? A revision of the literature.

Clinical and Experimental Medicine
Gabriele Di LorenzoGiovam Battista Rini

Abstract

The cause of chronic spontaneous urticaria has been an enigma for decades, but the recognition of functional autoantibodies in some patients with the spontaneous chronic urticaria has opened up a new concept of autoimmune urticaria. Clinical and laboratory features are in keeping with an autoimmune aetiology for many patients with otherwise inexplicable disease, but there is still debate about the importance of functional autoantibodies in the disease pathogenesis, how to test them and the clinical implications for treatment and prognosis. This review will look at the evidence for there being an autoimmune subset of urticaria, the strengths and weaknesses of the available tests in current use.

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Citations

Dec 19, 2015·Journal of Cutaneous Medicine and Surgery·Natasha GatteyPeter R Hull
Jun 2, 2015·Journal of Korean Medical Science·Yoo Seob ShinHae-Sim Park
Jun 8, 2012·Clinical Reviews in Allergy & Immunology·Katherine Altman, Christopher Chang
Apr 17, 2016·Allergologia et immunopathologia·P C L DionigiW C N Forte

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