PMID: 8458817Feb 1, 1993Paper

Chronic stimulation-induced changes in mitochondria and performance in rat skeletal muscle

Journal of Applied Physiology
M Takahashi, D A Hood

Abstract

Chronic low-frequency (10-Hz) electrical stimulation was used to investigate mitochondrial biogenesis in rat tibialis anterior muscle. Succinate dehydrogenase and citrate synthase were used as mitochondrial enzymes, and cardiolipin (CL) was used as a phospholipid index of the inner membrane. Stimulation was via the peroneal nerve (24 h/day) for 1, 2, 3, 5, 7, 10, 14, 21, and 28 days (n = 3-9 rats/day). After each period, endurance performance was evaluated in situ. The contralateral side (CON) served as control nonstimulated muscle. Endurance performance gradually improved after 5 days of stimulation to approximately twofold higher than CON muscle beyond 10 days. Succinate dehydrogenase activity rose to 2.4-fold above CON muscle (4.8 +/- 0.2 U/g; n = 54) by 10 days (half time = 6.1 days) and then remained constant. Citrate synthase demonstrated a similar change. The improved performance with stimulation was correlated (r = 0.61, P < 0.05) to these increases in enzyme activities. CL concentration increased from CON (0.35 +/- 0.02 mumol/g; n = 30) to 3.6- and 3.8-fold above CON at 10 and 14 days (half time = 4.2 days). This increase in CL was greater (P < 0.05) than for either enzyme during the same period. These data are consist...Continue Reading

Citations

Nov 1, 1995·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·G E Hyde, E W Rubel
Jan 1, 1996·Medicine and Science in Sports and Exercise·M RezvaniD A Hood
Jan 14, 2003·Annual Review of Physiology·Christopher D Moyes, David A Hood
Sep 10, 2003·Sports Medicine·Isabella IrrcherDavid A Hood
Aug 23, 2007·American Journal of Physiology. Endocrinology and Metabolism·Didier LaurentJiaping Gao
Jan 5, 2008·Biogerontology·Pedro Alexandre FigueiredoJosé Alberto Duarte
Jul 30, 2016·The Biochemical Journal·David A HoodChris C W Chen
Aug 2, 2019·BioResearch Open Access·Anjali PatelKoyal Garg
Jun 5, 1998·The American Journal of Physiology·M TakahashiD A Hood
May 8, 2003·American Journal of Physiology. Cell Physiology·Isabella IrrcherDavid A Hood
Aug 6, 2004·The Proceedings of the Nutrition Society·David A Hood, Anna-Maria Joseph
Nov 25, 2003·Journal of Applied Physiology·Tanguy MarquestePatrick Decherchi
May 22, 2008·American Journal of Physiology. Endocrinology and Metabolism·Vladimir Ljubicic, David A Hood
Dec 12, 2012·Journal of Applied Physiology·Olga OstojicDavid A Hood
Nov 26, 2010·Journal of Speech, Language, and Hearing Research : JSLHR·Colleen A McMullenJoseph C Stemple
Apr 29, 2016·American Journal of Physiology. Cell Physiology·Jonathan M MemmeDavid A Hood
May 31, 2018·The Cochrane Database of Systematic Reviews·Kylie HillRoger Goldstein
May 18, 2004·Journal of Applied Physiology·Vladimir LjubicicDavid A Hood
Nov 19, 2005·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·Vladimir LjubicicDavid A Hood
Apr 9, 2010·American Journal of Physiology. Cell Physiology·Ruanne Y J LaiDavid A Hood
Nov 22, 2007·Aging Cell·Béatrice ChabiDavid A Hood
Jan 25, 2003·Medicine and Science in Sports and Exercise·David A HoodArne A Rungi
Dec 25, 2008·Physiological Genomics·Ayesha SaleemDavid A Hood
Nov 16, 2006·American Journal of Physiology. Endocrinology and Metabolism·Peter J AdhihettyDavid A Hood
Apr 27, 2004·Journal of Applied Physiology·Yuko YoshidaArend Bonen
Jan 29, 2010·American Journal of Physiology. Cell Physiology·Anna-Maria JosephDavid A Hood
Mar 21, 2012·Muscle & Nerve·Clement RouviereChristopher P Ingalls
Mar 1, 1994·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·D A HoodM Takahashi
Aug 21, 2008·Sports Medicine·José A LuminiAntónio Ascensão
Jan 27, 2006·American Journal of Physiology. Cell Physiology·Yen-Chih HuangKeith Baar
Jun 21, 2013·American Journal of Physiology. Cell Physiology·Yuan ZhangDavid A Hood
Mar 20, 2018·Skeletal Muscle·Chris Chin Wah ChenDavid A Hood
Jul 14, 2020·Frontiers in Physiology·Anna GumàAntonio Zorzano
Jul 17, 1999·The American Journal of Physiology·D FreyssenetD A Hood
Apr 9, 2021·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Scott D Kirkton, Ariella A Yazdani

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