Chronic toxicity of Gynostemma pentaphyllum

Fitoterapia
A AttawishP Chavalittumrong

Abstract

The effect of water extract of Gynostemma pentaphyllum was evaluated on 6-month chronic toxicity in Wistar rats. Control group received orally 10 ml kg(-1) day(-1). The extract was orally given to the five treatment groups at the doses of 6, 30, 150, 750 and 750 mg kg(-1) day(-1) for 24 weeks. The last group served as the recovery group. The results showed that the extract did not produce any significant dose-related changes. Therefore, it is concluded that the extract of G. pentaphyllum at the given doses did not produce any significant toxic effect in rats during 6-month period of the treatment.

Citations

Nov 24, 2012·Journal of Agricultural and Food Chemistry·Jing-Guang LuZhi-Hong Jiang
Jun 11, 2008·The American Journal of Chinese Medicine·Wen-Chung HuangJiann-Jong Shen
May 3, 2007·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Wen-Chung HuangJiann-Jong Shen
May 17, 2014·International Journal of Biological Macromolecules·Jun LiuQing Qiao
Jul 9, 2011·Natural Product Reports·Ilze VermaakJosias H Hamman
Apr 16, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hyun Sook ChoiMyung Koo Lee
Mar 3, 2012·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·C MüllerL Schild
Jun 24, 2015·Bioorganic & Medicinal Chemistry Letters·Xiao-Shu ZhangYu-Qing Zhao
Mar 29, 2008·Journal of Ethnopharmacology·Ming-Ho ChenYi-Wen Liu
Oct 24, 2007·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·T H-W HuangB D Roufogalis
Jun 19, 2007·Phytochemistry·Zhengyi YangLihong Hu
Sep 13, 2005·Biochemical Pharmacology·Tom Hsun-Wei HuangBasil D Roufogalis
Sep 16, 2015·BMC Complementary and Alternative Medicine·Ting Ting ZhaoMyung Koo Lee
Feb 23, 2013·Journal of Nutrition and Metabolism·V T T HuyenC G Ostenson
Jun 26, 2013·Journal of Ethnopharmacology·Natthakarn ChiranthanutNirush Lertprasertsuk
Apr 5, 2011·Pharmacology, Biochemistry, and Behavior·Guanglin ZhangGuodong Gao
Dec 13, 2005·Journal of Ethnopharmacology·Mallika JainuC S Shyamala Devi
Apr 30, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hyun Sook ChoiMyung Koo Lee
Dec 28, 2007·The Journal of Reproduction and Development·Wichai CherdshewasartPorntipa Picha
Aug 17, 2019·Current Vascular Pharmacology·Hoa Thi PhuGianfranco Pintus
Oct 31, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hongmei ZangJun Li
Apr 23, 2020·Frontiers in Pharmacology·Abdullah ShaitoGianfranco Pintus
Nov 14, 2020·Journal of Ethnopharmacology·Ngoc-Hieu NguyenWon Keun Oh
Oct 29, 2016·Mitochondrial DNA. Part B, Resources·Xin-Yi ZengYing Li
Jul 19, 2008·Journal of Agricultural and Food Chemistry·Xingbin YangYun Ruan
Jul 30, 2021·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·Amanda RaoDavid Briskey

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.

Related Papers

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
C CircostaF Occhiuto
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
J CuiJ G Bruhn
Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
C RujjanawateD Amornlerdpison
© 2021 Meta ULC. All rights reserved