Chronic urticaria in Chinese population: a hospital-based multicenter epidemiological study

Allergy
H ZhongF Hao

Abstract

The epidemiologic profiles of chronic urticaria (CU) vary considerably among regions, and few such data are available from China. We performed a multicenter open questionnaire investigation about the clinical and laboratory features of CU, defined as recurrent wheals with/without angioedema lasting for ≥6 weeks, among 3027 patients. Female preponderance was observed (female/male ratio, 1.46 : 1). The mean age at diagnosis was 34.7 ± 13.8 years, and the mean disease duration was 18.5 ± 46.1 months (range, 1.5-127 months). Patients were classified as having chronic spontaneous urticaria (CSU, 61.0% of patients), physical urticaria (PU, 26.2%), or other urticaria types (OU, 2.3%). Nocturnal attacks were reported by 60% of cases. The Urticaria Activity Score (UAS) in patients with CSU was 3.8 ± 1.4. The mean Dermatology Life Quality Index was 7.3 ± 3.4 (range 0-30). Induction or exacerbation of wheals with alcohol drinking was reported by 55.7% of patients. Chronic hepatitis B was less prevalent in our CU patients compared with the general Chinese population (2.7% vs 7%). Positive autologous serum skin tests (ASSTs) were observed in 66.9% of patients. Patients with positive ASST had higher UAS, greater angioedema frequencies, longe...Continue Reading

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Citations

Oct 7, 2014·Allergy·C Schlapbach, D Simon
Apr 17, 2016·Allergologia et immunopathologia·P C L DionigiW C N Forte
Apr 29, 2014·The Journal of Allergy and Clinical Immunology·Jonathan A BernsteinDana Wallace
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Nov 7, 2017·The British Journal of Dermatology·Y S KimY M Park
Mar 11, 2016·PloS One·Shiu-Dong ChungChao-Hung Chen
Jul 25, 2020·Medicine·Shuai ZhouMingxin Xue
Aug 19, 2017·Chinese Journal of Integrative Medicine·Hiroyuki MurotaIchiro Katayama
Mar 30, 2019·Recent Patents on Inflammation & Allergy Drug Discovery·Kam L HonSteven K Loo
Oct 29, 2020·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Yuanyuan DingHongli An
Apr 26, 2021·The Journal of Allergy and Clinical Immunology. in Practice·Jonathan A BernsteinMaria Staevska

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